Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Chemically Crosslinked Nanogels of Pegylated Poly Ethyleneimine (L-Histidine Substituted) Synthesized Via Metal Ion Coordinated Self-Assembly for Delivery of Methotrexate: Cytocompatibility, Cellular Delivery and Antitumor Activity in Resistant Cells
Mehdi Esfandyari-Manesh
Mehdi Esfandyari-Manesh

Assistant Professor of Pharmaceutics

Nanotechnology Research Center

Tehran University of Medical Sciences

All Documents
1. 3D Printed Core/Shell Scaffold Based on Nano/Microspheric Hydrogel for Osteosarcoma Anticancer Delivery and Bone Regeneration, Journal of Drug Delivery Science and Technology (2025)
2. Alginate Scaffold Containing Triamcinolone Sustained Release Microsphere, Melatonin and Stem Cells for Cartilage Regeneration and Inflammation, BioNanoScience (2025)
3. Local Delivery of Ibrutinib by Folate Receptor-Mediated Targeting Plga–Peg Nanoparticles to Glioblastoma Multiform: In Vitro and in Vivo Studies, Journal of Drug Targeting (2025)
4. Recent Progress in Topical and Transdermal Approaches for Melanoma Treatment, Drug Delivery and Translational Research (2025)
5. Synergistic Effect of Yes-Associated Protein Sirna and Temozolomide Against Glioblastoma Using a Localized Nano Delivery System, International Journal of Biological Macromolecules (2025)
6. Utilizing Machine Learning for Predicting Drug Release From Polymeric Drug Delivery Systems, Computers in Biology and Medicine (2025)
7. Characterization Techniques for Advanced Research, Mesoporous Silica Nanoparticles: Drug Delivery, Catalysis and Sensing Applications (2024)
8. Local Multi-Drug Delivery and Osteogenesis in Bone Metastasis of Prostate Cancer by a Core-Shell 3D Printed Scaffold, Journal of Drug Delivery Science and Technology (2024)
9. Losartan in Situ Forming Gel As a New Treatment for Hypertrophic Scars, Aesthetic Plastic Surgery (2024)
10. Self-Assembled Nanoparticles of Alginate and Paclitaxel-Triphenylphosphonium for Mitochondrial Apoptosis Targeting, Medical Oncology (2024)
11. An Anti-Inflammatory Glyburide-Loaded Nanoghost for Atherosclerosis Therapy: A Red Blood Cell Based Bio-Mimetic Strategy, Giant (2023)
12. Corrigendum to “Dual Drug Delivery System of Plga Nanoparticles to Reverse Drug Resistance by Altering Bax/Bcl-2” [J. Drug Deliv. Sci. Technol. 47 (2018) 291–298, (S1773224718301825), (10.1016/J.Jddst.2018.07.019)], Journal of Drug Delivery Science and Technology (2023)
13. Development of Osteon-Like Scaffold-Cell Construct by Quadruple Coaxial Extrusion-Based 3D Bioprinting of Nanocomposite Hydrogel, Biomaterials Advances (2023)
14. Design and Optimization of Plga-Based Tribulus Terrestris Loaded Nanoparticles, Research Journal of Pharmacognosy (2022)
15. Impact of Oxygen-Calcium-Generating and Bone Morphogenetic Protein-2 Nanoparticles on Survival and Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells in the 3D Bio-Printed Scaffold, Colloids and Surfaces B: Biointerfaces (2022)
16. Improvement of in Vitro Osteogenesis and Anti-Infection Properties by Gelma Scaffold Containing Levofloxacin Nanoparticles and Strontium Microspheres for Osteomyelitis, Journal of Materials Science (2022)
17. Novel Biodegradable Molecularly Imprinted Polymer Nanoparticles for Drug Delivery of Methotrexate Anti-Cancer; Synthesis, Characterization and Cellular Studies, DARU# Journal of Pharmaceutical Sciences (2022)
18. Preparation and Characterization of Albumin Nanoparticles of Paclitaxel-Triphenylphosphonium Conjugates: New Approach to Subcellular Targeting, Drug research (2020)
19. S2p Peptide-Conjugated Plga-Maleimide-Peg Nanoparticles Containing Imatinib for Targeting Drug Delivery to Atherosclerotic Plaques, DARU# Journal of Pharmaceutical Sciences (2020)
20. Enhancement Mitochondrial Apoptosis in Breast Cancer Cells by Paclitaxel-Triphenylphosphonium Conjugate in Dna Aptamer Modified Nanoparticles, Journal of Drug Delivery Science and Technology (2019)
21. Synthetic and Biological Identities of Polymeric Nanoparticles Influencing the Cellular Delivery: An Immunological Link, Journal of Colloid and Interface Science (2019)
22. Dual Drug Delivery System of Plga Nanoparticles to Reverse Drug Resistance by Altering Bax/Bcl-2, Journal of Drug Delivery Science and Technology (2018)
23. Peptide Functionalized Poly Ethylene Glycol-Poly Caprolactone Nanomicelles for Specific Cabazitaxel Delivery to Metastatic Breast Cancer Cells, Materials Science and Engineering C (2017)
24. Targeted Delivery of Cabazitaxel by Conjugation to Albumin-Peg-Folate Nanoparticles Using a Cysteine-Acrylate Linker and Simple Synthesis Conditions, Current Drug Delivery (2017)
25. Delivery of Disulfiram Into Breast Cancer Cells Using Folate-Receptor-Targeted Plga-Peg Nanoparticles: In Vitro and in Vivo Investigations, Journal of Nanobiotechnology (2016)
26. Enhanced Cytotoxicity to Cancer Cells by Codelivery and Controlled Release of Paclitaxel-Loaded Sirolimus-Conjugated Albumin Nanoparticles, Chemical Biology and Drug Design (2016)
27. Paclitaxel Molecularly Imprinted Polymer-Peg-Folate Nanoparticles for Targeting Anticancer Delivery: Characterization and Cellular Cytotoxicity, Materials Science and Engineering C (2016)
28. Pharmacokinetics and Bioavailability of Three Promising Tilmicosin-Loaded Lipid Nanoparticles in Comparison With Tilmicosin Phosphate Following Oral Administration in Broiler Chickens, Turkish Journal of Veterinary and Animal Sciences (2016)
29. Preparation and Characterization of Three Tilmicosin-Loaded Lipid Nanoparticles: Physicochemical Properties and In-Vitro Antibacterial Activities, Iranian Journal of Pharmaceutical Research (2016)
30. Preparation, Characterization and Evaluation of Drug Release Properties of Simvastatin-Loaded Plga Microspheres, Iranian Journal of Pharmaceutical Research (2016)
31. Specific Targeting Delivery to Muc1 Overexpressing Tumors by Albumin-Chitosan Nanoparticles Conjugated to Dna Aptamer, International Journal of Pharmaceutics (2016)
32. Aptamer Decorated Hyaluronan/Chitosan Nanoparticles for Targeted Delivery of 5-Fluorouracil to Muc1 Overexpressing Adenocarcinomas, Carbohydrate Polymers (2015)
33. Enhanced Cellular Cytotoxicity and Antibacterial Activity of 18-Β-Glycyrrhetinic Acid by Albumin-Conjugated Plga Nanoparticles, Drug Research (2015)
34. Improved Anticancer Delivery of Paclitaxel by Albumin Surface Modification of Plga Nanoparticles, DARU# Journal of Pharmaceutical Sciences (2015)
35. Protein Corona Hampers Targeting Potential of Muc1 Aptamer Functionalized Sn-38 Core-Shell Nanoparticles, International Journal of Pharmaceutics (2015)
36. Regulation of Bax/Bcl2 Gene Expression in Breast Cancer Cells by Docetaxel-Loaded Human Serum Albumin Nanoparticles, Medical Oncology (2015)