Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
The Effect of Fibronectin on Structural and Biological Properties of Single Walled Carbon Nanotube Publisher



Mottaghitalab F1 ; Farokhi M2 ; Atyabi F3 ; Omidvar R4 ; Shokrgozar MA4 ; Sadeghizadeh M5
Authors

Source: Applied Surface Science Published:2015


Abstract

Despite the attractive properties of carbon nanotubes (CNTs). cytoxicity and hydrophobicity are two main considerable features which limit their application in biomedical fields. It was well established that treating CNTs with extracellular matrix components could reduce these unfavourable characteristics. In an attempt to address these issues, fibronectin (FN) with different concentrations was loaded on single walled carbon nanotubes (SWCNTs) substrate. Scanning electron microscope, atomic force microscopy (AFM), contact angles and X-ray photoelectron spectroscopy (XPS) were preformed in order to characterize FN loaded SWCNTs substrates. According to XPS and AFM results. FN could interact with SWCNTs and for this, the hydrophilicity of SWCNTs was improved. Additionally. SWCNT modified with FN showed less cytotoxicity compared with neat SWCNT. Finally. FN was shown to act as an interesting extracellular component for enhancing the biological properties of SWCNT. © 2015 Elsevier B.V. All rights reserved.
Related Docs
View other Related Docs
1. The Effect of Fibronectin Coating on Protein Corona Structure and Cellular Uptake of Single-Walled Carbon Nanotubes, Precision Nanomedicine (2020)
2. Application of Carbon Nanotubes in Nanomedicine: New Medical Approach for Tomorrow, Medical Imaging: Concepts# Methodologies# Tools# and Applications (2016)
3. Biological Response to Carbon-Family Nanomaterials: Interactions at the Nano-Bio Interface, Frontiers in Bioengineering and Biotechnology (2019)
Experts (# of related papers)
View all Related Experts
Fatemeh Atyabi (3)
Rassoul Dinarvand (3)
Other Related Docs
4. An Insight Into the Toxicological Impacts of Carbon Nanotubes (Cnts) on Human Health: A Review, Environmental Advances (2024)
5. The Role of Single- and Multi-Walled Carbon Nanotube in Breast Cancer Treatment, Therapeutic Delivery (2020)
6. Application of Carbon Nanotubes for Controlled Release of Growth Factors or Endocannabinoids: A Breakthrough in Biomedicine, Biomedical Reviews (2016)
7. Interaction of Single and Multi Wall Carbon Nanotubes With the Biological Systems: Tau Protein and Pc12 Cells As Targets, Scientific Reports (2016)
8. Electrically Conductive Materials: Opportunities and Challenges in Tissue Engineering, Biomolecules (2019)
9. Prospects of Sirna Applications in Regenerative Medicine, International Journal of Pharmaceutics (2017)
10. Carbon Nanotubes in Microfluidic Lab-On-A-Chip Technology: Current Trends and Future Perspectives, Microfluidics and Nanofluidics (2017)
11. Conductive Biomaterials As Nerve Conduits: Recent Advances and Future Challenges, Applied Materials Today (2020)
12. Carbon Nanotubes Part Ii: A Remarkable Carrier for Drug and Gene Delivery, Expert Opinion on Drug Delivery (2015)
13. Bioelectronics of the Cellular Cytoskeleton: Monitoring Cytoskeletal Conductance Variation for Sensing Drug Resistance, ACS Sensors (2019)
14. Preparation of Diaminedicarboxyplatinum (Ii) Functionalized Single-Wall Carbon Nanotube Via Bingel Reaction As a Novel Cytotoxic Agent, Iranian Journal of Pharmaceutical Research (2016)
15. Fabrication of Poly(Ε-Caprolactone)/Paclitaxel (Core)/Chitosan/Zein/Multi-Walled Carbon Nanotubes/Doxorubicin (Shell) Nanofibers Against Mcf-7 Breast Cancer, Polymers for Advanced Technologies (2023)
16. Development of Electrically Conductive Hybrid Nanofibers Based on Cnt-Polyurethane Nanocomposite for Cardiac Tissue Engineering, Microscopy Research and Technique (2019)
17. Antibacterial Effect of Carbon Nanotube Containing Chemical Compounds on Drug-Resistant Isolates of Acinetobacter Baumannii, Iranian Journal of Microbiology (2021)
18. Biomimetic Engineered Approaches for Neural Tissue Engineering: Spinal Cord Injury, Journal of Biomedical Materials Research - Part B Applied Biomaterials (2023)
19. Effects of Amphotericin B-Conjugated Functionalized Carbon Nanoparticles in the Treatment of Cutaneous Leishmaniasis, Parasite Immunology (2024)
20. Multifunctional 3D Hierarchical Bioactive Green Carbon-Based Nanocomposites, ACS Sustainable Chemistry and Engineering (2021)