The Effect of Fibronectin Coating on Protein Corona Structure and Cellular Uptake of Single-Walled Carbon Nanotubes

The Effect of Fibronectin Coating on Protein Corona Structure and Cellular Uptake of Single-Walled Carbon Nanotubes Publisher

Mottaghitalab F¹ ; Kiani M² ; Farokhi M³ ; Dinarvand R^{1, 2} ; Ghodsollahi T⁴ ; Atyabi F^{1, 2}

Source: Precision Nanomedicine Published:2020

Abstract

Protein coating, as an outstanding surface modification strategy, influence the organization of biomolecules in the interface of nanomaterials. In the present study, fibronectin (FN) was used to modify die surface chemistry of single-walled carbon nanotubes (SWNTs) and carboxylated SWNTs (CC>2-SWNTs) to analyze its effects on the protein corona composition and cellular uptake. At first, the successful coating of FN on the surface of both SWNTs was confirmed by transmission electron microscopy (TEM) and Raman spectroscopy. The results showed that the biomolecular organization of SWNTs and CCh-SWNTs coronas was changed after FN coating based on the evidence obtained from the surface plasmon intensity of the samples. Moreover, the MTT assay and confocal microscopy imaging revealed less cytotoxicity and cellular uptake of SWNTs coronas in comparison to bulk samples, respectively. It is suggested that protein coating of SWNTs can modify the corona pattern and consequently the biological behavior of carbon nanotubes. © 2020, Andover House, Inc.. All rights reserved.

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Fatemeh Atyabi (4)

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Style	Citing Format
MLA	Mottaghitalab F, et al.. "The Effect of Fibronectin Coating on Protein Corona Structure and Cellular Uptake of Single-Walled Carbon Nanotubes." Precision Nanomedicine, vol. 3, no. 1, 2020, pp. 459-470.
APA	Mottaghitalab F, Kiani M, Farokhi M, Dinarvand R, Ghodsollahi T, Atyabi F (2020). The Effect of Fibronectin Coating on Protein Corona Structure and Cellular Uptake of Single-Walled Carbon Nanotubes. Precision Nanomedicine, 3(1), 459-470.
Chicago	Mottaghitalab F, Kiani M, Farokhi M, Dinarvand R, Ghodsollahi T, Atyabi F. "The Effect of Fibronectin Coating on Protein Corona Structure and Cellular Uptake of Single-Walled Carbon Nanotubes." Precision Nanomedicine 3, no. 1 (2020): 459-470.
Harvard	Mottaghitalab F et al. (2020) 'The Effect of Fibronectin Coating on Protein Corona Structure and Cellular Uptake of Single-Walled Carbon Nanotubes', Precision Nanomedicine, 3(1), pp. 459-470.
Vancouver	Mottaghitalab F, Kiani M, Farokhi M, Dinarvand R, Ghodsollahi T, Atyabi F. The Effect of Fibronectin Coating on Protein Corona Structure and Cellular Uptake of Single-Walled Carbon Nanotubes. Precision Nanomedicine. 2020;3(1):459-470.
BibTex	@article{ author = {Mottaghitalab F and Kiani M and Farokhi M and Dinarvand R and Ghodsollahi T and Atyabi F}, title = {The Effect of Fibronectin Coating on Protein Corona Structure and Cellular Uptake of Single-Walled Carbon Nanotubes}, journal = {Precision Nanomedicine}, volume = {3}, number = {1}, pages = {459-470}, year = {2020} }
RIS	TY - JOUR AU - Mottaghitalab F AU - Kiani M AU - Farokhi M AU - Dinarvand R AU - Ghodsollahi T AU - Atyabi F TI - The Effect of Fibronectin Coating on Protein Corona Structure and Cellular Uptake of Single-Walled Carbon Nanotubes JO - Precision Nanomedicine VL - 3 IS - 1 SP - 459 EP - 470 PY - 2020 ER -

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