Recent Progress in the Application of Amidines for the Synthesis of N-Heterocyclic Compounds

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Summary: Why are nitrogen compounds key in drugs? A study shows amidines help create vital bioactive molecules for medicines, advancing synthetic chemistry for new treatments. #DrugDiscovery #Chemistry

Doraghi F¹ ; Karimian S² ; Navid H³ ; Ghanbarlou M¹ ; Larijani B¹ ; Mahdavi M¹

Source: Monatshefte fur Chemie Published:2024

Abstract

Nitrogen-containing heterocycles are an inseparable part of many biologically active compounds. Therefore, the synthesis of these structures is of great importance in the field of synthetic chemistry. Due to the presence of two nitrogen atoms in the amidine structure, this molecule can be considered as a dual nucleophile in the synthesis of various heterocycles. The current review highlights recent advances in the application of amidines, in particular, N-arylamidines, as versatile precursors in transition metal-catalyzed, and metal-free reactions for the construction of N-heterocyclic compounds. Graphical abstract: (Figure presented.). © Springer-Verlag GmbH Austria, part of Springer Nature 2024.

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Style	Citing Format
MLA	Doraghi F, et al.. "Recent Progress in the Application of Amidines for the Synthesis of N-Heterocyclic Compounds." Monatshefte fur Chemie, vol. 155, no. 5, 2024, pp. 419-439.
APA	Doraghi F, Karimian S, Navid H, Ghanbarlou M, Larijani B, Mahdavi M (2024). Recent Progress in the Application of Amidines for the Synthesis of N-Heterocyclic Compounds. Monatshefte fur Chemie, 155(5), 419-439.
Chicago	Doraghi F, Karimian S, Navid H, Ghanbarlou M, Larijani B, Mahdavi M. "Recent Progress in the Application of Amidines for the Synthesis of N-Heterocyclic Compounds." Monatshefte fur Chemie 155, no. 5 (2024): 419-439.
Harvard	Doraghi F et al. (2024) 'Recent Progress in the Application of Amidines for the Synthesis of N-Heterocyclic Compounds', Monatshefte fur Chemie, 155(5), pp. 419-439.
Vancouver	Doraghi F, Karimian S, Navid H, Ghanbarlou M, Larijani B, Mahdavi M. Recent Progress in the Application of Amidines for the Synthesis of N-Heterocyclic Compounds. Monatshefte fur Chemie. 2024;155(5):419-439.
BibTex	@article{ author = {Doraghi F and Karimian S and Navid H and Ghanbarlou M and Larijani B and Mahdavi M}, title = {Recent Progress in the Application of Amidines for the Synthesis of N-Heterocyclic Compounds}, journal = {Monatshefte fur Chemie}, volume = {155}, number = {5}, pages = {419-439}, year = {2024} }
RIS	TY - JOUR AU - Doraghi F AU - Karimian S AU - Navid H AU - Ghanbarlou M AU - Larijani B AU - Mahdavi M TI - Recent Progress in the Application of Amidines for the Synthesis of N-Heterocyclic Compounds JO - Monatshefte fur Chemie VL - 155 IS - 5 SP - 419 EP - 439 PY - 2024 ER -

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