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Recent Advances in Synthesis and Transformations of 1,2,3-Benzotriazinones Publisher

Summary: Can a molecule lead to new drugs? Research shows 1,2,3-benzotriazinones create diverse compounds for medicines, advancing synthetic chemistry for treatments. #DrugDevelopment #Chemistry

Doraghi F1 ; Karimian S2 ; Larijani B1 ; Mahdavi M1
Authors

Source: Journal of Organometallic Chemistry Published:2024


Abstract

In recent years, 1,2,3-benzotriazinones have been recognized as an alternative nitrogen- containing framework in a series of annulations and cross-coupling reactions under transition metal catalysis, as well as metal-free systems. A wide array of N-heterocycles and ortho- functionalized benzamides could be constructed through transformations of 1,2,3- benzotriazinones by the extrusion of a benign N2 gas. This review highlights recent advancements on the synthetic methodologies and organic transformations of 1,2,3- benzotriazinones. © 2024
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