Solubility of Mesalazine in Polyethylene Glycol 400 + Water Mixtures at Different Temperatures

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Solubility of Mesalazine in Polyethylene Glycol 400 + Water Mixtures at Different Temperatures Publisher

Moradi M^{1, 2} ; Rahimpour E^{2, 3} ; Hemmati S⁴ ; Martinez F⁵ ; Barzegarjalali M⁶ ; Jouyban A^{2, 7}

Source: Journal of Molecular Liquids Published:2020

Abstract

Temperature-dependent solubility data for mesalazine in the binary system of polyethylene glycol 400 (PEG 400)/water are determined by a shake-flask method at 293.2–313.2 K. The solubility data are validated to five different computational models including the van't Hoff, the mixture response surface, the Yalkowsky, the Jouyban-Acree, and the Jouyban-Acree-van't Hoff. All the investigated models have good correlation and validation according to obtained the mean relative deviations (MRD%) for back-calculated data. Moreover, apparent thermodynamic analysis shows an endothermic process for mesalazine in (PEG 400 + water) mixtures. Further, based on inverse Kirkwood-Buff integrals is observed that mesalazine is preferentially solvated by PEG in all the mixtures. © 2020 Elsevier B.V.

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Style	Citing Format
MLA	Moradi M, et al.. "Solubility of Mesalazine in Polyethylene Glycol 400 + Water Mixtures at Different Temperatures." Journal of Molecular Liquids, vol. 314, no. , 2020, pp. -.
APA	Moradi M, Rahimpour E, Hemmati S, Martinez F, Barzegarjalali M, Jouyban A (2020). Solubility of Mesalazine in Polyethylene Glycol 400 + Water Mixtures at Different Temperatures. Journal of Molecular Liquids, 314(), -.
Chicago	Moradi M, Rahimpour E, Hemmati S, Martinez F, Barzegarjalali M, Jouyban A. "Solubility of Mesalazine in Polyethylene Glycol 400 + Water Mixtures at Different Temperatures." Journal of Molecular Liquids 314, no. (2020): -.
Harvard	Moradi M et al. (2020) 'Solubility of Mesalazine in Polyethylene Glycol 400 + Water Mixtures at Different Temperatures', Journal of Molecular Liquids, 314(), pp. -.
Vancouver	Moradi M, Rahimpour E, Hemmati S, Martinez F, Barzegarjalali M, Jouyban A. Solubility of Mesalazine in Polyethylene Glycol 400 + Water Mixtures at Different Temperatures. Journal of Molecular Liquids. 2020;314():-.
BibTex	@article{ author = {Moradi M and Rahimpour E and Hemmati S and Martinez F and Barzegarjalali M and Jouyban A}, title = {Solubility of Mesalazine in Polyethylene Glycol 400 + Water Mixtures at Different Temperatures}, journal = {Journal of Molecular Liquids}, volume = {314}, number = {}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Moradi M AU - Rahimpour E AU - Hemmati S AU - Martinez F AU - Barzegarjalali M AU - Jouyban A TI - Solubility of Mesalazine in Polyethylene Glycol 400 + Water Mixtures at Different Temperatures JO - Journal of Molecular Liquids VL - 314 IS - SP - EP - PY - 2020 ER -

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