Solubility of Sildenafil Citrate in the Binary Mixtures of Ethylene Glycol and Water at Different Temperatures

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Solubility of Sildenafil Citrate in the Binary Mixtures of Ethylene Glycol and Water at Different Temperatures Publisher

Hatefi A¹ ; Rahimpour E^{2, 3} ; Ghafourian T⁴ ; Martinez F⁵ ; Barzegarjalali M⁶ ; Jouyban A^{2, 7}

Source: Journal of Molecular Liquids Published:2020

Abstract

The aim of this work is to investigate the solubility behavior of sildenafil citrate (SC) in the binary mixtures of ethylene glycol and water at different temperatures in the range of 293.2–313.2 K. The generated data are correlated with some linear and non-linear cosolvency models including the van't Hoff, the double log-log, the mixture response surface, Yalkowsky, Jouyban-Acree, Jouyban-Acree-van't Hoff, and the modified Wilson models. The mean relative deviations (MRD%) of the back-calculated solubility for each applied models are computed as an accuracy criterion. Density data measured for SC saturated mixtures as another physico-chemical property are also correlated with the Jouyban-Acree model and the results are discussed. Furthermore, apparent thermodynamic properties for SC dissolution process are computed by using van't Hoff and Gibbs equations. © 2019 Elsevier B.V.

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Style	Citing Format
MLA	Hatefi A, et al.. "Solubility of Sildenafil Citrate in the Binary Mixtures of Ethylene Glycol and Water at Different Temperatures." Journal of Molecular Liquids, vol. 299, no. , 2020, pp. -.
APA	Hatefi A, Rahimpour E, Ghafourian T, Martinez F, Barzegarjalali M, Jouyban A (2020). Solubility of Sildenafil Citrate in the Binary Mixtures of Ethylene Glycol and Water at Different Temperatures. Journal of Molecular Liquids, 299(), -.
Chicago	Hatefi A, Rahimpour E, Ghafourian T, Martinez F, Barzegarjalali M, Jouyban A. "Solubility of Sildenafil Citrate in the Binary Mixtures of Ethylene Glycol and Water at Different Temperatures." Journal of Molecular Liquids 299, no. (2020): -.
Harvard	Hatefi A et al. (2020) 'Solubility of Sildenafil Citrate in the Binary Mixtures of Ethylene Glycol and Water at Different Temperatures', Journal of Molecular Liquids, 299(), pp. -.
Vancouver	Hatefi A, Rahimpour E, Ghafourian T, Martinez F, Barzegarjalali M, Jouyban A. Solubility of Sildenafil Citrate in the Binary Mixtures of Ethylene Glycol and Water at Different Temperatures. Journal of Molecular Liquids. 2020;299():-.
BibTex	@article{ author = {Hatefi A and Rahimpour E and Ghafourian T and Martinez F and Barzegarjalali M and Jouyban A}, title = {Solubility of Sildenafil Citrate in the Binary Mixtures of Ethylene Glycol and Water at Different Temperatures}, journal = {Journal of Molecular Liquids}, volume = {299}, number = {}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Hatefi A AU - Rahimpour E AU - Ghafourian T AU - Martinez F AU - Barzegarjalali M AU - Jouyban A TI - Solubility of Sildenafil Citrate in the Binary Mixtures of Ethylene Glycol and Water at Different Temperatures JO - Journal of Molecular Liquids VL - 299 IS - SP - EP - PY - 2020 ER -

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