Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline

Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline Publisher

Tahermansouri H¹ ; Mirosanloo A¹ ; Keshel SH² ; Gardaneh M³

Source: Carbon Letters Published:2016

Abstract

The attachment of 2-aminobenzamide to carboxylated multi-wall carbon nanotubes (MWCNTs)- COOH was achieved through the formation of amide bonds. Then, the functionalized MWCNTs, MWCNT-amide, were treated by phosphoryl chloride to produce MWCNT-quin. The products were characterized by Fourier transform infrared spectroscopy, Raman spectroscopy, scanning electron microscopy, thermogravimetric analysis, derivative thermogravimetric, steady-state fluorescence spectroscopy, and solubility testing. MWCNT-quin showed photo-electronic properties, which is due to the attachment of the 4-hydroxyquinazoline groups to them as proved by steady-state fluorescence spectroscopy. This suggests intramolecular interactions between the tubes and the attached 4-hydroxyquinazoline. The toxicity of the samples was evaluated in human embryonic kidney HEK293 and human breast cancer SKBR3 cell lines, and the viable cell numbers were measured by 3-(4,5-dimethyl- 2-thiazolyl)-2,5-diphenyltetrazolium bromide (MTT) after the cells were cultured for 24 h. Cellular investigations showed that the modified MWCNTs, particularly MWCNT-quin, have considerably significant toxic impact on SKBR3 as compared to HEK293 at the concentration of 5 μg/mL. © Korean Carbon Society.

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Style	Citing Format
MLA	Tahermansouri H, et al.. "Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline." Carbon Letters, vol. 17, no. 1, 2016, pp. 45-52.
APA	Tahermansouri H, Mirosanloo A, Keshel SH, Gardaneh M (2016). Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline. Carbon Letters, 17(1), 45-52.
Chicago	Tahermansouri H, Mirosanloo A, Keshel SH, Gardaneh M. "Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline." Carbon Letters 17, no. 1 (2016): 45-52.
Harvard	Tahermansouri H et al. (2016) 'Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline', Carbon Letters, 17(1), pp. 45-52.
Vancouver	Tahermansouri H, Mirosanloo A, Keshel SH, Gardaneh M. Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline. Carbon Letters. 2016;17(1):45-52.
BibTex	@article{ author = {Tahermansouri H and Mirosanloo A and Keshel SH and Gardaneh M}, title = {Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline}, journal = {Carbon Letters}, volume = {17}, number = {1}, pages = {45-52}, year = {2016} }
RIS	TY - JOUR AU - Tahermansouri H AU - Mirosanloo A AU - Keshel SH AU - Gardaneh M TI - Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline JO - Carbon Letters VL - 17 IS - 1 SP - 45 EP - 52 PY - 2016 ER -

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