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Status and Future Scope of Plant-Based Green Hydrogels in Biomedical Engineering Publisher



Mohammadinejad R1 ; Maleki H2 ; Larraneta E3 ; Fajardo AR4 ; Nik AB5 ; Shavandi A6 ; Sheikhi A7, 8, 9, 10, 11 ; Ghorbanpour M12 ; Farokhi M13 ; Govindh P14 ; Cabane E15, 16 ; Azizi S17 ; Aref AR18 ; Mozafari M19, 20, 21 Show All Authors
Authors
  1. Mohammadinejad R1
  2. Maleki H2
  3. Larraneta E3
  4. Fajardo AR4
  5. Nik AB5
  6. Shavandi A6
  7. Sheikhi A7, 8, 9, 10, 11
  8. Ghorbanpour M12
  9. Farokhi M13
  10. Govindh P14
  11. Cabane E15, 16
  12. Azizi S17
  13. Aref AR18
  14. Mozafari M19, 20, 21
  15. Mehrali M22
  16. Thomas S14
  17. Mano JF23
  18. Mishra YK24
  19. Thakur VK25, 26

Source: Applied Materials Today Published:2019


Abstract

Hydrogels are the most iconic class of soft materials, and since their first report in the literature, they have attracted the attention of uncountable researchers. Over the past two decades, hydrogels have become smart and sophisticated materials with numerous applications. This class of soft materials have been playing a significant role in biomedicine due to their tunable and often programmable properties. Hydrogels from renewable polymers have been popularized in biomedical applications as they are often biocompatible, easily accessible, and inexpensive. The challenge however has been to find an ideal plant-based hydrogel for biomedicine that can mimic critical properties of human tissues in terms of structure, function, and performance. In addition, natural polymers can readily be functionalized to engineer their chemical and physical uproperties pertinent to drug delivery and tissue engineering. Here, the most recent advances in the synthesis, fabrication, and applications of plant-based hydrogels in biomedical engineering are reviewed. We cover essential and updated information about plants as green sources of biopolymers for hydrogel synthesis, general aspects of hydrogels and plant-based hydrogels, and thorough discussion regarding the use of such hydrogels in the biomedical engineering area. Furthermore, this review details the present status of the field and answers several important questions about the potential of plant-based hydrogels in advanced biomedical applications including therapeutics, tissue engineering, wound dressing, and diagnostics., etc. © 2019 Elsevier Ltd
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