Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Th9 Cells As a New Player in Inflammatory Skin Disorders Publisher Pubmed



Jadali Z1
Authors

Source: Iranian Journal of Allergy# Asthma and Immunology Published:2019


Abstract

CD4+T cells are composed of different subpopulations that differ in developmental pathways, surface markers, and their products. Among the catalog of these cells is Th9 cell subset that has a great capacity of Interleukin (IL)-9 production. They could be involved in the pathogenic or protective immune responses. Therefore, it is important to know how Th9 cells and cytokines influence the function of the human immune system as multitasking machinery, both in isolation or after the interaction with other surroUnding cells. Since an important characteristic of Th9 cells is their tropism for skin, this article reviews the physiological and pathophysiological functions of Th9 and its cytokines Under normal conditions and inflammatory skin disorders. © Copyright© April 2019, Iran J Allergy Asthma Immunol. All rights reserved.
Related Docs
View other Related Docs
1. Features and Roles of T Helper 9 Cells and Interleukin 9 in Immunological Diseases, Allergologia et Immunopathologia (2019)
2. T Helper-9 Cells and Interleukin-9 in Transplantation: The Open Question, Human Immunology (2022)
3. Inborn Errors of Immunity Reveal Molecular Requirements for Generation and Maintenance of Human Cd4+ Il-9–Expressing Cells, Journal of Allergy and Clinical Immunology (2025)
Experts (# of related papers)
View all Related Experts
Nima Rezaei (4)
Mohammad Hossein Nicknam (1)
Other Related Docs
4. The Roles of Cd4+ T-Cells in Tumor Immunity, Cancer Immunology: A Translational Medicine Context# Second Edition (2020)
5. T-Helper 22 Cells As a New Player in Chronic Inflammatory Skin Disorders, International Journal of Dermatology (2015)
6. Il9 Single Nucleotide Polymorphism and Serum Levels of Interleukin 9 in Children With Asthma, Pediatric# Allergy# Immunology# and Pulmonology (2016)
7. Emerging Cytokines in Allergic Airway Inflammation: A Genetic Update, Current Immunology Reviews (2016)
8. The Molecular Mechanisms of Vitamin a Deficiency in Multiple Sclerosis, Journal of Molecular Neuroscience (2016)
9. A Role for Th1-Like Th17 Cells in the Pathogenesis of Inflammatory and Autoimmune Disorders, Molecular Immunology (2019)
10. The Potential Roles of Th17 Cells in the Pathogenesis of Oral Lichen Planus, Inflammation Research (2023)
11. The Imbalance of Circulating T Helper Subsets and Regulatory T Cells in Patients With Lrba Deficiency: Correlation With Disease Severity, Journal of Cellular Physiology (2018)
12. Il-22 Produced by T Helper Cell 22 As a New Player in the Pathogenesis of Immune Thrombocytopenia, Endocrine# Metabolic and Immune Disorders - Drug Targets (2015)
13. A Systematic Review of Interleukin-17 in Oral Lichen Planus: From Etiopathogenesis to Treatment, Clinical Medicine and Research (2023)
14. Tgf-Β and Th17 Cells Related Injuries in Patients With Sulfur Mustard Exposure, Journal of Cellular Physiology (2018)
15. The Toll-Like Receptor 2 (Tlr2)-Related Immunopathological Responses in the Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis, Iranian Journal of Allergy# Asthma and Immunology (2019)
16. The Newly Identified T Helper 22 Cells Lodge in Leukemia, International Journal of Hematology-Oncology and Stem Cell Research (2015)
17. The Pivotal Role of Cd69 in Autoimmunity, Journal of Autoimmunity (2020)
18. T Helper Cell Type-1 Transcription Factor T-Bet Is Down-Regulated in Type 1 Diabetes, Iranian Journal of Allergy# Asthma and Immunology (2016)
19. Asthma and Allergy, Clinical Immunology (2022)
20. The Modulatory Effects of Vitamin D on the Expression of Il-12 and Tgf-Β in the Spinal Cord and Serum of Mice With Experimental Autoimmune Encephalomyelitis, Iranian Journal of Pathology (2018)