Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Epigenetic Drugs As New Emerging Therapeutics: What Is the Scale's Orientation of Application and Challenges?
Pantea Izadi

Associate Professor of Medical Genetics

Department Medical Genetics

School of Medicine

Metabolomics and Genomics Research Center

Endocrinology and Metabolism Research Institute

Tehran University of Medical Sciences

All Documents
1. Estrogen-Insensitivity Syndrome (Eis) in a Female Adolescent Patient – a Case Report, Journal of Pediatric Endocrinology and Metabolism (2024)
2. Role of the Neanderthal Genome in Genetic Susceptibility to Covid-19: 3P21.31 Locus in the Spotlight, Biochemical Genetics (2024)
3. The Association of Rs17713054 With Neanderthal Origin at 3P21.31 Locus With the Severity of Covid-19 in Iranian Patients, Scientific Reports (2024)
4. Bioinformatics Analysis Reveals Novel Differentially Expressed Genes Between Ectopic and Eutopic Endometrium in Women With Endometriosis, Journal of Obstetrics and Gynecology of India (2023)
5. Tmprss2 Polymorphism (Rs12329760) and the Severity of the Covid-19 in Iranian Population, PLoS ONE (2023)
6. The Association of Ace I/D Polymorphism With the Severity of Covid-19 in Iranian Patients: A Case-Control Study, Human Gene (2022)
7. The Association of Apoe Genotype With Covid-19 Disease Severity, Scientific Reports (2022)
8. The Expression Levels of Circulating Mir-129 and Mir-203A in Association With Breast Cancer and Related Metastasis, Iranian Journal of Public Health (2022)
9. A Methylation Signature at the Cpg Island Promoter of Estrogen Receptor Beta (Er-Β) in Breasts of Women May Be an Early Footmark of Lack of Breastfeeding and Nulliparity, Pathology Research and Practice (2021)
10. A Panel of Plasma Mirnas 199B-3P, 224-5P and Let-7D-3P As Non-Invasive Diagnostic Biomarkers for Endometriosis, Reproductive Sciences (2021)
11. Assessment of Dapk1 and Cavin3 Gene Promoter Methylation in Breast Invasive Ductal Carcinoma and Metastasis, Cell Journal (2021)
12. Correction To: A Panel of Plasma Mirnas 199B-3P, 224-5P, and Let-7D-3P As Non-Invasive Diagnostic Biomarkers for Endometriosis (Reproductive Sciences, (2021), 28, 4, (991-999), 10.1007/S43032-020-00415-Z), Reproductive Sciences (2021)
13. The Role of Mirnas 340-5P, 92A-3P, and 381-3P in Patients With Endometriosis: A Plasma and Mesenchymal Stem-Like Cell Study, BioMed Research International (2021)
14. Influence of Plasma Circulating Exosomes Obtained From Obese Women on Tumorigenesis and Tamoxifen Resistance in Mcf-7 Cells, IUBMB Life (2020)
15. Resveratrol Alleviates Non-Alcoholic Fatty Liver Disease Through Epigenetic Modification of the Nrf2 Signaling Pathway, International Journal of Biochemistry and Cell Biology (2020)
16. Changes in Fto and Irx3 Gene Expression in Obese and Overweight Male Adolescents Undergoing an Intensive Lifestyle Intervention and the Role of Fto Genotype in This Interaction, Journal of Translational Medicine (2019)
17. Early Parity Epigenetic Footprint of Foxa1 Gene Body in Normal Breast Tissue of Iranian Women, Iranian Biomedical Journal (2019)
18. Interactions Between Macro-Nutrients’ Intake, Fto and Irx3 Gene Expression, and Fto Genotype in Obese and Overweight Male Adolescents, Adipocyte (2019)
19. Methylation of Progesterone Receptor Isoform a Promoter in Normal Breast Tissue: An Epigenetic Link Between Early Age at Menarche and Risk of Breast Cancer?, Journal of Cellular Biochemistry (2019)
20. The Role of Fto Genotype in the Association Between Fto Gene Expression and Anthropometric Measures in Obese and Overweight Adolescent Boys, American Journal of Men's Health (2019)
21. Up-Regulation of Fto Gene Expression Was Associated With Increase in Skeletal Muscle Mass in Overweight Male Adolescents, Archives of Medical Science (2019)
22. A Complete Linkage Disequilibrium in a Haplotype of Three Snps in Fat Mass and Obesity Associated (Fto) Gene Was Strongly Associated With Anthropometric Indices After Controlling for Calorie Intake and Physical Activity, BMC Medical Genetics (2018)
23. A Haplotype of Three Snps in Fto Had a Strong Association With Body Composition and Bmi in Iranian Male Adolescents, PLoS ONE (2018)
24. A Link Between Expression Level of Long-Non-Coding Rna Zfas1 in Breast Tissue of Healthy Women and Obesity, International Journal of Biological Markers (2018)
25. Comparison of Brca1 Expression Between Triple-Negative and Luminal Breast Tumors, Iranian Biomedical Journal (2018)
26. Expression Levels of Breast Cancer-Related Gas5 and Lsinct5 Lncrnas in Cancer-Free Breast Tissue: Molecular Associations With Age at Menarche and Obesity, Breast Journal (2018)
27. Parp-1 Overexpression As an Independent Prognostic Factor in Adult Non-M3 Acute Myeloid Leukemia, Genetic Testing and Molecular Biomarkers (2018)
28. Radioprotective Effect of Melatonin on Expression of Cdkn1a and Rad50 Genes in Rat Peripheral Blood, Journal of Cancer Research and Therapeutics (2018)
29. Significance of Egfr Mrna Expression in Luminal and Triple Negative Breast Tumors, International Journal of Cancer Management (2018)
30. The Association Between Parp1 and Lig3 Expression Levels and Chromosomal Translocations in Acute Myeloid Leukemia Patients, Cell Journal (2018)
31. Effects of Maternal Isocaloric Diet Containing Different Amounts of Soy Oil and Extra Virgin Olive Oil on Weight, Serum Glucose, and Lipid Profile of Female Mice Offspring, Iranian Journal of Medical Sciences (2017)
32. Epigenetic Changes of the Esr1 Gene in Breast Tissue of Healthy Women: A Missing Link With Breast Cancer Risk Factors?, Genetic Testing and Molecular Biomarkers (2017)
33. Expression Levels of Two Dna Repair-Related Genes Under 8 Gy Ionizing Radiation and 100 Mg/Kg Melatonin Delivery in Rat Peripheral Blood, Journal of Biomedical Physics and Engineering (2017)
34. Methylomics of Breast Cancer: Seeking Epimarkers in Peripheral Blood of Young Subjects, Tumor Biology (2017)
35. Modulation of Radiation-Induced Base Excision Repair Pathway Gene Expression by Melatonin, Journal of Medical Physics (2017)
36. New Methods in the Diagnosis of Cancer and Gene Therapy of Cancer Based on Nanoparticles, Cancer Gene Therapy (2017)
37. The High Frequency of Pik3ca Mutations in Iranian Breast Cancer Patients, Cancer Investigation (2017)
38. Coinhibition of Overexpressed Genes in Acute Myeloid Leukemia Subtype M2 by Gold Nanoparticles Functionalized With Five Antisense Oligonucleotides and One Anti-Cd33(+)/Cd34(+) Aptamer, Cancer Gene Therapy (2016)
39. Extra Virgin Olive Oil in Maternal Diet In, But High Amount Has Deleterious Effects Creases Osteogenic Genes Expression on Bones in Mice Offspring at Adolescence, Iranian Journal of Basic Medical Sciences (2016)
40. Femtomolar Level Detection of Rassf1a Tumor Suppressor Gene Methylation by Electrochemical Nano-Genosensor Based on Fe3o4/Tmc/Au Nanocomposite and Pt-Modified Electrode, Biosensors and Bioelectronics (2016)
41. Candidate Gene Biodosimeters of Mice and Human Exposure to Ionizing Radiation by Quantitative Reverse Transcription Polymerase Chain Reaction, Journal of Cancer Research and Therapeutics (2015)
42. Dna Methylation As a Promising Landscape: A Simple Blood Test for Breast Cancer Prediction, Tumor Biology (2015)
43. Epigenetics and Three Main Clinical Aspects of Breast Cancer Management, Epigenetics Territory and Cancer (2015)