Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Phytochemical Analysis, Antimicrobial, Antioxidant Activities and Total Phenols of Ferulago Carduchorum in Two Vegetative Stages (Flower and Fruit) Pubmed



Golfakhrabadi F1 ; Ardekani MRS1, 2 ; Saeidnia S3 ; Yousefbeyk F4 ; Jamalifar H5 ; Ramezani N1 ; Akbarzadeh T2, 6 ; Khanavi M1, 7
Authors

Source: Pakistan Journal of Pharmaceutical Sciences Published:2016


Abstract

Ferulago carduchorum (Apiaceae family) is an endemic plant of Iran. The crude extract and four fractions of aerial parts of F. carduchorum in two vegetative stages (flower and fruit) were studied for their total phenolic contents, antimicrobial and antioxidant activities using folin-ciocalteu assay, micro dilution method and DPPH assay, respectively. The results indicated that the best antioxidant activity was determined in flower crude extract (IC50=0.44mg/mL). The flower ethyl acetate fraction (FLE) showed better antimicrobial and antifungal activities than other fractions. So, FLE was selected for phytochemical investigations, resulting in isolation of a flavonoid (hesperetin). Hesperetin showed antimicrobial activity. The results showed that the antimicrobial and antioxidant effects during the flowering are obviously more than the fruit season.
Related Docs
View other Related Docs
1. Biological Activities and Composition of Ferulago Carduchorum Essential Oil, Journal of Arthropod-Borne Diseases (2015)
2. In Vitro Antimicrobial and Acetylcholinesterase Inhibitory Activities of Coumarins From Ferulago Carduchorum, Medicinal Chemistry Research (2016)
3. A Review of the Ethnomedicinal, Phytochemical, and Pharmacological Properties of the Ferulago Genus Based on Structure–Activity Relationship (Sar) of Coumarins, DARU, Journal of Pharmaceutical Sciences (2024)
Experts (# of related papers)
View all Related Experts
Abbas Hadjiakhoondi (7)
Mahnaz Khanavi (6)
Other Related Docs
4. Gas Chromatography, Gc/Mass Analysis and Bioactivity of Essential Oil From Aerial Parts of Ferulago Trifida: Antimicrobial, Antioxidant, Ache Inhibitory, General Toxicity, Mtt Assay and Larvicidal Activities, Journal of Arthropod-Borne Diseases (2017)
5. Antioxidant and Antiacetylcholinesterase Activity of Teucrium Hyrcanicum, Pharmacognosy Research (2015)
6. Strong Insecticidal Potential of Methanol Extract of Ferulago Trifida Fruits Against Anopheles Stephensi As Malaria Vector, Environmental Science and Pollution Research (2019)
7. Evaluation of the Total Antioxidant Capacity of Oliveria Decumbens and Capparis Spinosa, Journal of Biological Research (Italy) (2022)
8. In Vitro Antioxidant and Free Radical Scavenging Activity of Four Alkanna Species Growing in Iran, Pharmacognosy Research (2015)
9. Compositions of Essential Oils and Some Biological Properties of Stachys Laxa Boiss. & Buhse and S. Byzantina K. Koch, Research Journal of Pharmacognosy (2021)
10. Essential Oil Analysis and Isolation of Coumarins and Flavonol Glycosides of Ferulago Angulata (Schltdl.) Boiss. Fruits, Pharmaceutical Sciences (2021)
11. Antioxidant and Larvicidal Activity of Areal Parts of Scrophularia Striata Against Malaria Vector Anopheles Stephensi, Journal of Arthropod-Borne Diseases (2018)
12. Bioactive Coumarins From the Roots and Fruits of Ferulago Trifida Boiss., an Endemic Species to Iran, Natural Product Research (2018)
13. Determination and Evaluating the Antioxidant Properties of Ziziphus Nummularia (Burm.F.) Wight & Arn., Crataegus Pontica K.Koch and Scrophularia Striata Boiss, Egyptian Journal of Veterinary Science(Egypt) (2022)
14. Chemical Constituents From the Fruits of Ferula Ovina (Boiss.) Boiss. and Their Chemotaxonomic Significance, Biochemical Systematics and Ecology (2023)
15. Ferula Assa-Foetida Fruits: Antioxidant Activity, Toxicity Potential and Phytochemical Constituents, Research Journal of Pharmacognosy (2025)
16. Investigation of Phenolic Compounds and Antioxidant Activity of Leaves Extracts From Seventeen Cultivars of Iranian Olive (Olea Europaea L.), Journal of Food Science and Technology (2018)
17. Evaluation of Antioxidant and Antibacterial Effects of the Biologically Active Metabolites From the Leaves of Ferulago Trifida Boiss, Iranian Journal of Chemistry and Chemical Engineering (2024)
18. Biological Evaluation of the Isolated Compounds From Methanol Fraction of Leutea Avicennia Mozaff, Iranian Journal of Pharmaceutical Research (2018)
19. Isolation of Phenolic Derivatives and Essential Oil Analysis of Prangos Ferulacea (L.) Lindl. Aerial Parts, Iranian Journal of Pharmaceutical Research (2017)
20. Antioxidant Activity and Phytochemical Screening of Ficus Benghalensis Aerial Roots Fractions, Journal of Reports in Pharmaceutical Sciences (2019)