Monogenic Mutations Associated With Iga Deficiency

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Monogenic Mutations Associated With Iga Deficiency Publisher Pubmed

Abolhassani H^{1, 2} ; Aghamohammadi A² ; Hammarstrom L¹

Source: Expert Review of Clinical Immunology Published:2016

Abstract

Introduction: For twenty years, two paradigms have been considered as the main genetic contributors to immunoglobulin A deficiency, including cytogenetic defects involving large chromosomal aberrations and an association with the human major histocompatibility complex (MHC) locus. However, an overview of recent studies suggests a role for several monogenic disorders in the development of this disease. Areas covered: This review examines the concept of monogenic disorders for patients with IgA deficiency in order to identify the underlying pathogenic mechanism(s). Expert commentary: A clinical/immunologic workup followed by targeted gene mutation analysis has been proposed for an approach to IgA deficient patients. © 2016 Informa UK Limited, trading as Taylor & Francis Group.

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Style	Citing Format
MLA	Abolhassani H, Aghamohammadi A, Hammarstrom L. "Monogenic Mutations Associated With Iga Deficiency." Expert Review of Clinical Immunology, vol. 12, no. 12, 2016, pp. 1321-1335.
APA	Abolhassani H, Aghamohammadi A, Hammarstrom L (2016). Monogenic Mutations Associated With Iga Deficiency. Expert Review of Clinical Immunology, 12(12), 1321-1335.
Chicago	Abolhassani H, Aghamohammadi A, Hammarstrom L. "Monogenic Mutations Associated With Iga Deficiency." Expert Review of Clinical Immunology 12, no. 12 (2016): 1321-1335.
Harvard	Abolhassani H, Aghamohammadi A, Hammarstrom L (2016) 'Monogenic Mutations Associated With Iga Deficiency', Expert Review of Clinical Immunology, 12(12), pp. 1321-1335.
Vancouver	Abolhassani H, Aghamohammadi A, Hammarstrom L. Monogenic Mutations Associated With Iga Deficiency. Expert Review of Clinical Immunology. 2016;12(12):1321-1335.
BibTex	@article{ author = {Abolhassani H and Aghamohammadi A and Hammarstrom L}, title = {Monogenic Mutations Associated With Iga Deficiency}, journal = {Expert Review of Clinical Immunology}, volume = {12}, number = {12}, pages = {1321-1335}, year = {2016} }
RIS	TY - JOUR AU - Abolhassani H AU - Aghamohammadi A AU - Hammarstrom L TI - Monogenic Mutations Associated With Iga Deficiency JO - Expert Review of Clinical Immunology VL - 12 IS - 12 SP - 1321 EP - 1335 PY - 2016 ER -

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