Tehran University of Medical Sciences

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Rezaei N1, 2 ; De Vries E3, 4 ; Gambineri E5, 6 ; Meyts I7 ; Haddad E8
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Source: Stiehm's Immune Deficiencies: Inborn Errors of Immunity Published:2020


Abstract

Primary immune deficiencies are a heterogeneous group of inherited disorders generally caused by specific gene mutations affecting the immune system and leading to various clinical manifestations, including severe infections, autoimmunity, and malignancies. In this chapter, general considerations on primary immune deficiency as well as the various circumstances in which a primary immune deficiency is evoked are described. This chapter serves as a roadmap to understand the layout of this book and it mirrors the clinical approach taken by immunologists. © 2020 Elsevier Inc. All rights reserved.
1. Clinical Immunology, Clinical Immunology (2022)
2. Predominantly Antibody Deficiencies, Inborn Errors of Immunity: A Practical Guide (2021)
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