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Hexyltriphenylphosphonium Bromide As an Absolutely Chemoselective Ionic Liquid Catalyst in the Three-Component Reaction of Aryl Aldehydes, Acetophenones and Malononitrile Publisher



Bahrami K1 ; Khodaei MM1 ; Batooie N1 ; Hosseinzadeh N2 ; Foroumadi A3
Authors

Source: ChemistrySelect Published:2019


Abstract

Hexyltriphenylphosphonium bromide (HTPB) is used as an efficient ionic liquid catalyst in the chemoselective addition of malononitrile to carbonyl group moiety of chalcones through the three-component reaction of aryl aldehydes, acetophenone derivatves, and malononitrile to produce (E)-2-(1,3-diarylallylidene)malononitriles at ambient temperature. The method is simple, solvent-free, environmentally friendly, and gives excellent yields in a short reaction times. © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim