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Innate Lymphoid Cell Subsets and Their Cytokines in Autoimmune Diseases Publisher Pubmed



Maleki A1 ; Khanmiri JM1 ; Eshrat Abadi MK1 ; Soveyzi F2 ; Moazzami B3, 4 ; Hamblin MR5, 6 ; Rezaei N3, 4, 7
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Source: European Cytokine Network Published:2020


Abstract

Both the innate and adaptive arms of the immune system are involved in the development of autoimmune diseases. The main mechanism of disease is due to adaptive immune cells that are active against self-antigens. These cells can cause major damage to body tissues. Innate lymphoid cells (ILCs) are an important type of innate immune cell, whose role has been highlighted in recent years. ILCs are responsible for some of the inflammation in the pathogenesis of autoimmune diseases. In this review, we discuss the role of ILCs in the immune response, as well as their involvement in various autoimmune diseases. © 2020, JLE/Springer.
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