Controlled Release of Fluorouracil (5-Fu) From Chitosan-Co-Poly(Ethylene Glycol)/ Poly(Glycerol Sebacate)-Co-Poly(Ethylene Glycol)-Coated Iron Oxide

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Controlled Release of Fluorouracil (5-Fu) From Chitosan-Co-Poly(Ethylene Glycol)/ Poly(Glycerol Sebacate)-Co-Poly(Ethylene Glycol)-Coated Iron Oxide Publisher

Naghizadeh S¹ ; Hassanzadeh Nemati N¹ ; Hassani Najafabadi A² ; Niknejad H³ ; Khani MM^{3, 4}

Source: International Journal of Polymeric Materials and Polymeric Biomaterials Published:2018

Abstract

A blend of polyglycerol sebacate-poly ethylene glygol/chitosan-poly ethylene glycol-coated iron oxide (PGS-PEG/CS-PEG@Fe3O4) nanoparticles for 5FU delivery was prepared by reverse ultrasonic emulsification method. To enhance polymers’ solubility, PEG was grafted. Chemical characterization was performed through Fourier transformed infrared and proton nuclear magnetic resonance spectra. In vitro assay revealed that release profile of 5FU-loaded PGS-PEG/CS-PEG@Fe3O4 is sustained. Moreover, cytotoxicity was analyzed on HT29 cell line at the presence of external magnetic field using the lactate dehydrogenase and Alamar Blue. Results illustrate that (PGS-PEG/CS-PEG@Fe3O4) is promising to use as a carrier for 5FU anticancer agent with sustained tailored release. © 2017 Taylor & Francis.

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Style	Citing Format
MLA	Naghizadeh S, et al.. "Controlled Release of Fluorouracil (5-Fu) From Chitosan-Co-Poly(Ethylene Glycol)/ Poly(Glycerol Sebacate)-Co-Poly(Ethylene Glycol)-Coated Iron Oxide." International Journal of Polymeric Materials and Polymeric Biomaterials, vol. 67, no. 4, 2018, pp. 212-220.
APA	Naghizadeh S, Hassanzadeh Nemati N, Hassani Najafabadi A, Niknejad H, Khani MM (2018). Controlled Release of Fluorouracil (5-Fu) From Chitosan-Co-Poly(Ethylene Glycol)/ Poly(Glycerol Sebacate)-Co-Poly(Ethylene Glycol)-Coated Iron Oxide. International Journal of Polymeric Materials and Polymeric Biomaterials, 67(4), 212-220.
Chicago	Naghizadeh S, Hassanzadeh Nemati N, Hassani Najafabadi A, Niknejad H, Khani MM. "Controlled Release of Fluorouracil (5-Fu) From Chitosan-Co-Poly(Ethylene Glycol)/ Poly(Glycerol Sebacate)-Co-Poly(Ethylene Glycol)-Coated Iron Oxide." International Journal of Polymeric Materials and Polymeric Biomaterials 67, no. 4 (2018): 212-220.
Harvard	Naghizadeh S et al. (2018) 'Controlled Release of Fluorouracil (5-Fu) From Chitosan-Co-Poly(Ethylene Glycol)/ Poly(Glycerol Sebacate)-Co-Poly(Ethylene Glycol)-Coated Iron Oxide', International Journal of Polymeric Materials and Polymeric Biomaterials, 67(4), pp. 212-220.
Vancouver	Naghizadeh S, Hassanzadeh Nemati N, Hassani Najafabadi A, Niknejad H, Khani MM. Controlled Release of Fluorouracil (5-Fu) From Chitosan-Co-Poly(Ethylene Glycol)/ Poly(Glycerol Sebacate)-Co-Poly(Ethylene Glycol)-Coated Iron Oxide. International Journal of Polymeric Materials and Polymeric Biomaterials. 2018;67(4):212-220.
BibTex	@article{ author = {Naghizadeh S and Hassanzadeh Nemati N and Hassani Najafabadi A and Niknejad H and Khani MM}, title = {Controlled Release of Fluorouracil (5-Fu) From Chitosan-Co-Poly(Ethylene Glycol)/ Poly(Glycerol Sebacate)-Co-Poly(Ethylene Glycol)-Coated Iron Oxide}, journal = {International Journal of Polymeric Materials and Polymeric Biomaterials}, volume = {67}, number = {4}, pages = {212-220}, year = {2018} }
RIS	TY - JOUR AU - Naghizadeh S AU - Hassanzadeh Nemati N AU - Hassani Najafabadi A AU - Niknejad H AU - Khani MM TI - Controlled Release of Fluorouracil (5-Fu) From Chitosan-Co-Poly(Ethylene Glycol)/ Poly(Glycerol Sebacate)-Co-Poly(Ethylene Glycol)-Coated Iron Oxide JO - International Journal of Polymeric Materials and Polymeric Biomaterials VL - 67 IS - 4 SP - 212 EP - 220 PY - 2018 ER -

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