Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Controlling Cell Behavior Through the Design of Biomaterial Surfaces: A Focus on Surface Modification Techniques Publisher



Amani H1 ; Arzaghi H2 ; Bayandori M1 ; Dezfuli AS3, 4 ; Pazokitoroudi H5 ; Shafiee A6, 7 ; Moradi L8
Authors

Source: Advanced Materials Interfaces Published:2019


Abstract

Surface interaction at the biomaterial–cell interface is essential for a variety of cellular functions, such as adhesion, proliferation, and differentiation. Nevertheless, changes in the biointerface enable to trigger specific cell signaling and result in different cellular responses. In order to manufacture biomaterials with higher functionality, biomaterials containing immobilized bioactive ligands have been widely introduced and employed for tissue engineering and regenerative medicine applications. Moreover, a number of physical and chemical strategies have been used to improve the functionality of biomaterials and specifically at the material interface. Here, the interactions between materials and cells at the interface levels are described. Then, the importance of surface properties in cell function is discussed and recent methods for surface modifications are systematically highlighted. Additionally, the impact of bulk material properties on the cellular responses is briefly reviewed. © 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Other Related Docs
4. Nano-Immunoengineering: Opportunities and Challenges, Current Opinion in Biomedical Engineering (2019)
6. Selective Contribution of Bioactive Glasses to Molecular and Cellular Pathways, ACS Biomaterials Science and Engineering (2020)
11. Mussel-Inspired Polydopamine-Coated Silk Fibroin As a Promising Biomaterial, Bioinspired# Biomimetic and Nanobiomaterials (2020)
20. Smart Nanostructures for Cargo Delivery: Uncaging and Activating by Light, Journal of the American Chemical Society (2017)