A Review on the Role of Mir-576 in Human Disorders

Science Communicator Platform

Share By

A Review on the Role of Mir-576 in Human Disorders Publisher

Soleimani A ; Ahmadi M ; Sanati M ; Adabi H ; Ghafourifard S

Source: Human Gene Published:2025

Abstract

MicroRNAs (miRNAs) have pivotal role in post-transcriptional gene regulation by binding to target mRNAs, resulting in their degradation or translational repression. They contribute to the pathogenesis of several disorders, including cancer, autoimmune conditions and metabolic disorders. Among these non-coding transcripts is miR-576, a miRNA with dual roles in tumorigenesis and significant participation in non-malignant conditions. Through modulation of key cellular processes such as proliferation, apoptosis, migration, and immune responses, this miRNA participates in the pathoetiology of a variety of human disorders. This manuscript aims to comprehensively review the current understanding of miR-576 in malignant and non-malignant disorders, emphasizing its mechanistic roles, clinical implications, and therapeutic potential. By integrating the current knowledge on its role, we offer insights into the dual nature of miR-576 in disease pathogenesis and discover future directions for research and therapeutic development. © 2025 Elsevier B.V., All rights reserved.

Related Docs

View other Related Docs

1. The Importance of Mirna-630 in Human Diseases With an Especial Focus on Cancers, Cancer Cell International (2022)

2. Function of Mirna-145–5P in the Pathogenesis of Human Disorders, Pathology Research and Practice (2022)

3. Diagnostic, Prognostic, and Therapeutic Significance of Mir-139-5P in Cancers, Life Sciences (2020)

Experts (# of related papers)

View all Related Experts

Amir Ali Hamidieh (1)

Mohammad Hossein Modarressi (1)

Other Related Docs

4. Dysregulation of Mir-638 in Breast Cancer Patients and Bioinformatics Investigation of Its Target Genes in Apoptosis, Angiogenesis and Autophagy Pathways, International Journal of Cancer Management (2019)

5. An Overview of Micrornas: Biology, Functions, Therapeutics, and Analysis Methods, Journal of Cellular Physiology (2019)

6. Microrna-181 Serves As a Dual-Role Regulator in the Development of Human Cancers, Free Radical Biology and Medicine (2020)

7. A Review on the Role of Mirna-324 in Various Diseases, Frontiers in Genetics (2022)

8. Modulation of Micrornas Expression and Cellular Signaling Pathways Through Curcumin As a Potential Therapeutical Approach Against Ovarian Cancer: A Review, Pathology Research and Practice (2023)

9. Circulating Mirnas Can Serve As Potential Diagnostic Biomarkers in Chronic Myelogenous Leukemia Patients, Leukemia Research Reports (2021)

10. Microrna-184 in the Landscape of Human Malignancies: A Review to Roles and Clinical Significance, Cell Death Discovery (2023)

11. The Role of Micrornas in Myeloproliferative Neoplasia, International Journal of Hematology-Oncology and Stem Cell Research (2016)

12. Microrna a New Gate in Cancer and Human Disease: A Review, Journal of Biological Sciences (2017)

13. The Effect of Microrna-375 Overexpression, an Inhibitor of Helicobacter Pylori-Induced Carcinogenesis, on Lncrna Sox2ot, Jundishapur Journal of Microbiology (2016)

14. Cell Type-Dependent Functions of Microrna-92A, Journal of Cellular Biochemistry (2018)

15. Microrna-181A in Acute Lymphoblastic Leukemia: Expression Pattern, Target Genes and Its Potential As a Biomarker, Biochemistry and Biophysics Reports (2026)

16. Mirnas and Exosomal Mirnas in Lung Cancer: New Emerging Players in Tumor Progression and Therapy Response, Pathology Research and Practice (2023)

17. Wnt Pathway Targeting Reduces Triple-Negative Breast Cancer Aggressiveness Through Mirna Regulation in Vitro and in Vivo, Journal of Cellular Physiology (2019)

18. Micrornas in Non-Malignant Diseases, Synthesis Lectures on Biomedical Engineering (2022)

19. Lysophosphatidic Acid Signaling and Micrornas: New Roles in Various Cancers, Frontiers in Oncology (2022)

20. Micrornas in Lung Diseases: Recent Findings and Their Pathophysiological Implications, Pulmonary Pharmacology and Therapeutics (2015)

Style	Citing Format
MLA	Soleimani A, et al.. "A Review on the Role of Mir-576 in Human Disorders." Human Gene, vol. 46, no. , 2025, pp. -.
APA	Soleimani A, Ahmadi M, Sanati M, Adabi H, Ghafourifard S (2025). A Review on the Role of Mir-576 in Human Disorders. Human Gene, 46(), -.
Chicago	Soleimani A, Ahmadi M, Sanati M, Adabi H, Ghafourifard S. "A Review on the Role of Mir-576 in Human Disorders." Human Gene 46, no. (2025): -.
Harvard	Soleimani A et al. (2025) 'A Review on the Role of Mir-576 in Human Disorders', Human Gene, 46(), pp. -.
Vancouver	Soleimani A, Ahmadi M, Sanati M, Adabi H, Ghafourifard S. A Review on the Role of Mir-576 in Human Disorders. Human Gene. 2025;46():-.
BibTex	@article{ author = {Soleimani A and Ahmadi M and Sanati M and Adabi H and Ghafourifard S}, title = {A Review on the Role of Mir-576 in Human Disorders}, journal = {Human Gene}, volume = {46}, number = {}, pages = {-}, year = {2025} }
RIS	TY - JOUR AU - Soleimani A AU - Ahmadi M AU - Sanati M AU - Adabi H AU - Ghafourifard S TI - A Review on the Role of Mir-576 in Human Disorders JO - Human Gene VL - 46 IS - SP - EP - PY - 2025 ER -

Science Communicator Platform

Authors

Abstract