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Multi-Stimuli-Responsive Hydrogels for Therapeutic Systems: An Overview on Emerging Materials, Devices, and Drugs Publisher Pubmed



Hr Garshasbi Hamid REZA ; S Soleymani SINA ; Sm Naghib Seyed MORTEZA ; Mr Mozafari M R
Authors

Source: Current Pharmaceutical Design Published:2024


Abstract

The rising interest in hydrogels nowadays is due to their usefulness in physiological conditions as multi-stimuli-responsive hydrogels. To reply to the prearranged stimuli, including chemical triggers, light, magnetic field, electric field, ionic strength, temperature, pH, and glucose levels, dual/multi-stimuli-sensitive gels/hydrogels display controllable variations in mechanical characteristics and swelling. Recent attention has focused on injectable hydrogel-based drug delivery systems (DDS) because of its promise to offer regulated, controlled, and targeted medication release to the tumor site. These technologies have great potential to improve treatment outcomes and lessen side effects from prolonged chemotherapy exposure. © 2024 Elsevier B.V., All rights reserved.
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