Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Injectable Hydrogel-Based Drug Delivery Systems for Local Cancer Therapy Publisher Pubmed



Norouzi M1, 2 ; Nazari B3 ; Miller DW1, 4
Authors

Source: Drug Discovery Today Published:2016


Abstract

Common chemotherapy is often associated with adverse effects in normal cells and tissues. As an alternative approach, localized chemotherapy can diminish the toxicity of systemic chemotherapy while providing a sustained release of the chemotherapeutics at the target tumor site. Therefore, injectable biodegradable hydrogels as drug delivery systems for chemotherapeutics have become a matter of importance. Here, we review the application of a variety of injectable hydrogel-based drug delivery systems, including thermosensitive, pH-sensitive, photosensitive, dual-sensitive, as well as active targeting hydrogels, for the treatment of different types of cancer. Generally, injectable hydrogel-based drug delivery systems are found to be more efficacious than the conventional systemic chemotherapy in terms of cancer treatment. © 2016 Elsevier Ltd
1. Electrospun-Based Systems in Cancer Therapy, Electrospun Materials for Tissue Engineering and Biomedical Applications: Research# Design and Commercialization (2017)
Experts (# of related papers)
Other Related Docs
6. The Use of Nanoparticles As a Promising Therapeutic Approach in Cancer Immunotherapy, Artificial Cells# Nanomedicine and Biotechnology (2016)
14. Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery, Smart internal stimulus-responsive nanocarriers for drug and gene delivery (2015)
19. Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery, Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (2015)
20. Drug Delivery Systems, Drug Delivery Systems (2017)