Special Issues Related to The Diagnosis and Management of Acquired Aplastic Anemia in Countries With Restricted Resources, A Report on Behalf of the Eastern Mediterranean Blood and Marrow Transplantation (Embmt) Group and Severe Aplastic Anemia Working Party of the European Society for Blood and Marrow Transplantation (Saawp of Ebmt) Publisher Pubmed



Iftikhar R¹ ; Ahmad P¹ ; De Latour R² ; Dufour C³ ; Risitano A^{4, 5} ; Chaudhri N⁶ ; Bazarbachi A⁷ ; De La Fuente J⁸ ; Hochsmann B⁹ ; Osman Ahmed S⁶ ; Gergis U¹⁰ ; Elhaddad A¹¹ ; Halkes C¹² ; Albeirouti B¹³ Show All Authors
Source: Bone Marrow Transplantation Published:2021

Abstract

Aplastic anemia is a relatively rare but potentially fatal disorder, with a reported higher incidence in developing countries in comparison to the West. There are significant variations in epidemiological as well as etiological factors of bone marrow failure syndromes in the developing countries in comparison to the developed world. Furthermore, the management of bone marrow failure syndromes in resource constraint settings has significant challenges including delayed diagnosis and referral, limited accessibility to healthcare facilities, treatment modalities as well as limitations related to patients who require allogeneic stem cell transplantation. Here we will provide a review of the available evidence related to specific issues of aplastic anemia in the developing countries and we summarize suggested recommendations from the Eastern Mediterranean blood and bone marrow transplantation (EMBMT) group and the severe aplastic anemia working party of the European Society of blood and marrow transplantation (SAAWP of EBMT) related to the diagnosis and therapeutic options in countries with restricted resources. © 2021, The Author(s), under exclusive licence to Springer Nature Limited.