Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
An Update on Diabetic Kidney Disease, Oxidative Stress and Antioxidant Agents Publisher



Mahmoodnia L1 ; Aghadavod E2 ; Beigrezaei S3 ; Rafieiankopaei M4
Authors

Source: Journal of Renal Injury Prevention Published:2017


Abstract

Diabetes mellitus is a metabolic disease that is defined by relative or absolute deficiency of insulin secretion. Diabetic kidney disease seems to be one of the most frequent complications of diabetes mellitus. Based on evidence, increased free-radical formation and/or diminished antioxidant defenses induce oxidative stress that is implicated in the pathogenesis of diabetic kidney disease. It is evident that diabetic state induces oxidative stress through different signaling pathways as well as reactive oxygen species (ROS) formation that attributes to the activation of various downstream signaling cascade leading to structural the way to structural and functional changes in kidney. © 2017 The Author(s).
Related Docs
View other Related Docs
1. Role of Oxidative Stress and Inflammatory Factors in Diabetic Kidney Disease, Iranian Journal of Kidney Diseases (2016)
2. The Role of P66shc in Diabetes: A Comprehensive Review From Bench to Bedside, Journal of Diabetes Research (2022)
3. Moderate Exercise Attenuates Caspase-3 Activity, Oxidative Stress, and Inhibits Progression of Diabetic Renal Disease in Db/Db Mice, American Journal of Physiology - Renal Physiology (2009)
Experts (# of related papers)
View all Related Experts
Azar Baradaran (4)
Shiva Seirafian (2)
Other Related Docs
4. Effect of Probiotics on Oxidative Stress and Inflammatory Status in Diabetic Nephropathy: A Systematic Review and Meta-Analysis of Clinical Trials, Heliyon (2021)
5. Effect of the Administration of Solanum Nigrum Fruit on Prevention of Diabetic Nephropathy in Streptozotocin-Induced Diabetic Rats, Pharmacognosy Research (2017)
6. Mir-802-5P Is a Key Regulator in Diabetic Kidney Disease, Journal of Research in Medical Sciences (2023)
7. Molecular Aspects of Pancreatic Β-Cell Dysfunction: Oxidative Stress, Microrna, and Long Noncoding Rna, Journal of Cellular Physiology (2019)
8. Protection of Renal Tubular Cells by Antioxidants: Current Knowledge and New Trends, Cell Journal (2015)
9. Association of Serum Uric Acid With Proteinuria in Type 2 Diabetic Patients, Journal of Research in Medical Sciences (2013)
10. Metformin and Renal Protection, Journal of Isfahan Medical School (2014)
11. Renal Biochemical and Histopathological Alterations of Diabetic Rats Under Treatment With Hydro Alcoholic Morus Nigra Extract, Journal of Renal Injury Prevention (2017)
12. Comparative Study of Nephroprotective Effects of Resveratrol and Silymarin in Diabetic Rats; an Experimental Histopathologic Study, Journal of Nephropharmacology (2024)
13. Comparison of Ox-Ldl Levels in Diabetic Patients With Normo-, Micro-, and Macroalbuminuria With Their First Degree Relatives and the Healthy Control Group, International Journal of Endocrinology (2012)
14. A Combination of Herbal Compound (Sptc) Along With Exercise or Metformin More Efficiently Alleviated Diabetic Complications Through Down-Regulation of Stress Oxidative Pathway Upon Activating Nrf2-Keap1 Axis in Age Rich Diet-Induced Type 2 Diabetic Mice, Nutrition and Metabolism (2021)
15. Pretreatment Effect of D-Limonene on Oxidative Stress Induced by Renal Ischemia-Reperfusion Injury in Rats, Journal of Babol University of Medical Sciences (2022)
16. Antioxidant Therapy in Hemodialysis Patients, Journal of Isfahan Medical School (2014)
17. Allopourinol Effect on Reducing Proteinuria in Diabetic Retinopathy, Journal of Isfahan Medical School (2010)
18. A Systematic Integrative Approach Reveals Novel Micrornas in Diabetic Nephropathy, Journal of Research in Medical Sciences (2020)
19. Astaxanthin Prevents Nephrotoxicity Through Nrf2/Ho-1 Pathway, Canadian Journal of Physiology and Pharmacology (2024)
20. Effect of Allopurinol in Decreasing Proteinuria in Type 2 Diabetic Patients, Iranian Journal of Kidney Diseases (2010)