Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Copper-Catalyzed Synthesis of 2,3-Disubstituted Quinazolin-4(3H)-Ones From Benzyl-Substituted Anthranilamides Publisher



Foroumadi P1 ; Lotfi V2 ; Mahdavi M3 ; Moghimi S4 ; Soheilizad M5 ; Kianmehr E6 ; Firoozpour L6 ; Asadipour A1 ; Foroumadi A1
Authors

Source: Heterocyclic Communications Published:2018


Abstract

An efficient, practical approach to the copper-catalyzed synthesis of 2,3-disubstituted quinazolin-4(3H)-one derivatives is described. The preparation involves treatment of benzyl amines with benzyl anthranilamides in the presence of Cu(OAc)2 and tetra-n-butylammonium bromide (TBAB). © 2018 Walter de Gruyter GmbH, Berlin/Boston.
Related Docs
View other Related Docs
1. Isatoic Anhydride: A Fascinating and Basic Molecule for the Synthesis of Substituted Quinazolinones and Benzo Di/Triazepines, Current Organic Chemistry (2019)
2. Copper-Catalyzed Efficient Synthesis of 5-Arylindazolo[3,2-B]Quinazolin-7(5H)-Ones From 2-Nitrobenzaldehydes, Tetrahedron (2018)
3. A Novel and Efficient Synthesis of 2-Substituted Quinazolin-4(3H)-Ones by the Reaction of (Het)Arylmethanamines With Isatoic Anhydride, Tetrahedron Letters (2016)
Experts (# of related papers)
View all Related Experts
Mohammad Mahdavi (19)
Alireza Foroumadi (8)
Other Related Docs
4. Synthesis of Quinazolin-4(3H)-Ones Via the Reaction of Isatoic Anhydride With Benzyl Azides in the Presence of Potassium Tert-Butoxide in Dmso, Chemistry of Heterocyclic Compounds (2019)
5. Green Synthesis of 2-((2-Aryl-3-Oxoisoindolin-1-Yl)Methyl)Quinazolin-4(3H)-Ones Via Sequential Condensation, Sp3 C–H Bond Functionalization and Cyclization, Tetrahedron Letters (2018)
6. Pd-Catalyzed Carbonylation-Cyclization of N′-(2-Bromophenyl)Benzami-Dines by Chloroform As a Co Precursor for the Synthesis of Quinazolin-4(3H)-Ones, Letters in Organic Chemistry (2020)
7. Cubr/Et3n-Promoted Reactions of 2-Aminobenzamides and Isothiocyanates: Efficient Synthesis of Novel Quinazolin-4(3H)-Ones, Helvetica Chimica Acta (2016)
8. Efficient Synthesis of 3-Alkyl-2-(-1H-1,2,3-Triazolyl)Methyl)Thio)-2,3-Dihydroquinazolin-4(1H)-One Derivative Via Multistep Synthesis Approach by Novel Cu@Py-Oxa@Spion Catalyst, BMC Chemistry (2023)
9. Copper Supported Onto Magnetic Nanoparticles As an Efficient Catalyst for the Synthesis of Triazolobenzodiazepino[7,1-B]Quinazolin-11(9H)-Ones Via Click N-Arylation Reactions, ChemistrySelect (2021)
10. An Efficient, Four-Component Reaction for the Synthesis of Novel Carbamodithioates, Journal of Sulfur Chemistry (2017)
11. Synthesis of Novel Fused Quinazolinone Derivatives, Molecular Diversity (2016)
12. Copper-Supported Β-Cyclodextrin-Functionalized Magnetic Nanoparticles: Efficient Multifunctional Catalyst for One-Pot ‘Green’ Synthesis of 1,2,3-Triazolylquinazolinone Derivatives, Applied Organometallic Chemistry (2018)
13. Copper-Mediated Direct Cyanatation of Benzamides: A New Approach to the Synthesis of Quinazolinediones, European Journal of Organic Chemistry (2020)
14. An Efficient Four-Step Approach Toward Fused Triazino[1,6-A] Quinazolines, Combinatorial Chemistry and High Throughput Screening (2016)
15. A Convenient Method for the Synthesis of Chromeno[4,3-B]Pyridines Via Three-Component Reaction, Combinatorial Chemistry and High Throughput Screening (2018)
16. Efficient Synthesis of 2-Methylenethiazolo[2,3- B ]Quinazolinone Derivatives, Synlett (2015)
17. Copper Catalyst-Supported Modified Magnetic Chitosan for the Synthesis of Novel 2-Arylthio-2,3-Dihydroquinazolin-4(1H)-One Derivatives Via Chan–Lam Coupling, Inorganics (2022)
18. Unconventional Approaches for Synthesis of 2-Substituted Benzothiazoles, Organic and Biomolecular Chemistry (2025)
19. Synthesis and Cytotoxicity of Novel Thioxo-Quinazolino[3,4-A]Quinazolinones, Turkish Journal of Chemistry (2017)
20. A Novel Copper-Catalyzed Preparation of Pyrido[1,2- a ]Pyrimidine Derivatives, Synlett (2016)