Tehran University of Medical Sciences

Science Communicator Platform

Share By
Immunotherapy for Breast Cancer Treatment Publisher Pubmed



Simonian M1 ; Ghaffari MH1 ; Negahdari B1
Authors

Source: Iranian Biomedical Journal Published:2021


Abstract

Breast cancer, as a heterogeneous disease, includes a wide range of pathological and clinical behaviors. Current treatment protocols, including radiotherapy, chemotherapy, and hormone replacement therapy, are mainly associated with poor response and high rate of recurrence. Therefore, more efforts are needed to develop alternative therapies for this type of cancer. Immunotherapy, as a novel strategy in cancer treatment, has a potential in treating breast cancer patients. Although breast cancer has long been considered problematic to treat with immunotherapy, as it is immunologically cold, numerous newer preclinical and clinical reports now recommend that immunotherapy has the capability to treat breast cancer patients. In this review, we highlight the different immunotherapy strategies in breast cancer treatment. © 2021, Pasteur Institute of Iran. All rights reserved.
Related Docs
View other Related Docs
1. The Therapeutic Potential of Targeting Tumor Microenvironment and Modulation of Immunotherapy in Gastrointestinal Cancer, Current Cancer Drug Targets (2025)
2. Recent Progress in Cancer Immunotherapy: Overview of Current Status and Challenges, Pathology Research and Practice (2023)
3. Breast Cancer: Biology, Biomarkers, and Treatments, International Immunopharmacology (2020)
Experts (# of related papers)
View all Related Experts
Nima Rezaei (3)
Babak Arjmand (2)
Other Related Docs
4. Gene Therapy As an Emerging Therapeutic Approach to Breast Cancer: New Developments and Challenges, Human Gene Therapy (2021)
5. Immunotherapeutic Approaches for Cancer Therapy: An Updated Review, Artificial Cells# Nanomedicine and Biotechnology (2016)
6. Cell-Based Vaccines: Frontiers in Medical Technology for Cancer Treatment, Regenerative Engineering and Translational Medicine (2024)
7. Therapeutic Role and Immunogenic Characteristics of Cancer Testis Antigens in Breast Cancer: A Review, Cell Journal (2025)
8. Targeted Cancer Therapy: Review Article, Tehran University Medical Journal (2018)
9. Breast Cancer in the Era of Precision Medicine, Molecular Biology Reports (2022)
10. Gene Therapy: A Promising Approach for Breast Cancer Treatment, Cell Biochemistry and Function (2022)
11. Adcs, As Novel Revolutionary Weapons for Providing a Step Forward in Targeted Therapy of Malignancies, Current Drug Delivery (2020)
12. Antibody-Drug Conjugates: Possibilities and Challenges, Avicenna Journal of Medical Biotechnology (2019)
13. Clinical Perspective: Antibody-Drug Conjugates for the Treatment of Her2-Positive Breast Cancer, Molecular Therapy (2023)
14. Chimeric Antigen Receptor T-Cell Therapy for Breast Cancer, Future Oncology (2021)
15. Recent Progress in Immunotherapy of Breast Cancer Targeting the Human Epidermal Growth Factor Receptor 2 (Her2), Journal of Oncology Pharmacy Practice (2021)
16. Immunotherapeutic Approaches in Cancer, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2019)
17. Immunotherapeutic Approaches in Cancer, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2018)
18. Novel Trastuzumab-Dm1 Conjugate: Synthesis and Bio-Evaluation, Journal of Cellular Physiology (2019)
19. Combination Therapy of Macromolecules and Small Molecules: Approaches, Advantages, and Limitations, Nanostructures for Cancer Therapy (2017)
20. Breast Cancer Immunotherapy: Current and Novel Approaches, International Immunopharmacology (2021)