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Simple Design of an Aligned Transparent Biofilm by Magnetic Particles and Its Cellular Study Publisher



Heidari K S1 ; Biazar E2 ; Seyedbarzegar SM3 ; Mousavi N2 ; Vosoughi F2 ; Khademi S N2 ; Nami F2 ; Hosseinkazemi H4
Authors

Source: Polymers for Advanced Technologies Published:2017


Abstract

The aim of this study was to produce aligned biodegradable films. In this study, we used magnetic microparticles and strong magnetic field for orientation of gelatin gels. The samples were evaluated by microscopic analyses and cell culture assays with Schwann cells. Results of structural analyses showed a good arrangement and orientation of films under strong magnetic field with movement of magnetite particles. Cellular experiments showed a good cell adhesion and orientation on the designed films compared with those on unmodified ones. This aligned guide appears to have the right organization for testing in vivo nerve tissue engineering studies. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.
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