The Current Applications of Nano and Biomaterials in Drug Delivery of Dental Implant Publisher



Hakim LK¹ ; Yari A² ; Nikparto N³ ; Mehraban SH⁴ ; Cheperli S⁵ ; Asadi A⁶ ; Darehdor AA¹³ ; Nezaminia S¹⁴ ; Dortaj D⁷ ; Nazari Y⁸ ; Dehghan M⁹ ; Hojjat P¹⁰ ; Mohajeri M¹¹ ; Hasani Jebelli MS¹²
Source: BMC Oral Health Published:2024

Abstract

Background and aim: Dental implantology has revolutionized oral rehabilitation, offering a sophisticated solution for restoring missing teeth. Despite advancements, issues like infection, inflammation, and osseointegration persist. Nano and biomaterials, with their unique properties, present promising opportunities for enhancing dental implant therapies by improving drug delivery systems. This review discussed the current applications of nano and biomaterials in drug delivery for dental implants. Method: A literature review examined recent studies and advancements in nano and biomaterials for drug delivery in dental implantology. Various materials, including nanoparticles, biocompatible polymers, and bioactive coatings, were reviewed for their efficacy in controlled drug release, antimicrobial properties, and promotion of osseointegration. Results: Nano and biomaterials exhibit considerable potential in improving drug delivery for dental implants. Nanostructured drug carriers demonstrate enhanced therapeutic efficacy, sustained release profiles, and improved biocompatibility. Furthermore, bioactive coatings contribute to better osseointegration and reduced risks of infections. Conclusion: Integrating current nano and biomaterials in drug delivery for dental implants holds promise for advancing clinical outcomes. Enhanced drug delivery systems can mitigate complications associated with dental implant procedures, offering improved infection control, reduced inflammation, and optimized osseointegration. © 2024, The Author(s).