Tehran University of Medical Sciences

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A One-Pot Domino C-H, C-C Activation in Coumarins: A Fast Track to 2,3-Diaryl Benzo[B]Furans Publisher Pubmed



Khoobi M1 ; Molaverdi F2 ; Jafarpour F2 ; Abbasnia M2 ; Kubicki M3 ; Shafiee A1
Authors

Source: Chemical Communications Published:2015


Abstract

An approach to synthesize 2,3-diaryl benzo[b]furans using coumarins and aryl bromides is developed. This state-of-the-art strategy capitalizes on a palladium-catalyzed one-pot decarbonylative diarylation of coumarins, paving the way to achieve biologically interesting 2,3-diaryl benzo[b]furans. © The Royal Society of Chemistry 2015.