Tehran University of Medical Sciences

Science Communicator Platform

Share By
Therapeutic Potentials and Candidates for Covid-19 Publisher



Rezghi Rami M1 ; Meskini M2, 3, 4 ; Rezaei Khozani N5 ; Forouzandehdel S6 ; Momtaz S7, 8, 9 ; Ghosh S10 ; Rezaei N4, 11, 12 ; Abdolghaffari AH9, 13
Authors

Source: Iranian Journal of Science Published:2023


Abstract

The current coronavirus disease 2019 (COVID-19) outbreak spread rapidly worldwide. Yet, there is no identifiable antiviral treatment, so an effective drug is urgently needed. Preventive strategies and oxygen therapy are the main practical approaches to prevent and treat COVID-19. Clinical trials are in progress for the antiviral and immunomodulation agents that eventually are being developed for COVID-19 treatment. Pharmacological, immunotherapies, natural-based supplements, biologics, and combination therapies interventions have been established. The concept of drug repurposing was re-visited, and many conventional antivirals or immunosuppresses were evaluated for Efficacy against COVID-19 infection. Even though much has been published, the rapid progression of therapeutic strategies and unpredictable disease alterations necessitates continual information updates. This review defines drug repurposing and summarizes a medication developed for other therapeutic approaches rather than SARS-CoV-2 treatment. Furthermore, we provide data on the effectiveness of traditional Chinese medicines (TCM) on COVID-19. Additionally, biological and advanced Nano-based drug delivery systems are reviewed. © 2023, The Author(s), under exclusive licence to Shiraz University.
Related Docs
View other Related Docs
1. Therapeutic Strategies for Covid-19 Patients: An Update, Infectious Disorders - Drug Targets (2022)
2. Covid-19 Immunotherapy: Treatment Based on the Immune Cell-Mediated Approaches, International Immunopharmacology (2022)
3. A Narrative Literature Review on Traditional Medicine Options for Treatment of Corona Virus Disease 2019 (Covid-19), Complementary Therapies in Clinical Practice (2020)
Experts (# of related papers)
View all Related Experts
Nima Rezaei (4)
Azadeh Zarei (1)
Other Related Docs
4. Recent Advances in Passive Immunotherapies for Covid-19: The Evidence-Based Approaches and Clinical Trials, International Immunopharmacology (2022)
5. Overview of the Current Promising Approaches for the Development of an Effective Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2) Vaccine, International Immunopharmacology (2020)
6. Antiviral Therapy Inmanagement of Covid-19: A Systematic Review on Current Evidence, Archives of Academic Emergency Medicine (2020)
7. Epidemiological Study of Covid-19 in Iran and the World: A Review Study, Infectious Disorders - Drug Targets (2022)
8. The Emergence of Novel Coronavirus Disease, Global Treatment Update and Its Containment Strategies in Overpopulated Countries: A Review, Coronaviruses (2021)
9. Lifesaving Combined Treatment in a Rapidly Progressive Covid-19 Pneumonia Case With Extensive Lung Involvement, Biomedical and Biotechnology Research Journal (2020)
10. Therapeutic Uses of Antihistamines in the Management of Covid-19: A Narrative Review, Anti-Infective Agents (2023)
11. Monoclonal Antibody As a Potential Anti-Covid-19, Biomedicine and Pharmacotherapy (2020)
12. Phytopharmaceuticals Mediated Furin and Tmprss2 Receptor Blocking: Can It Be a Potential Therapeutic Option for Covid-19?, Phytomedicine (2021)
13. Nanobodies As Powerful Pulmonary Targeted Biotherapeutics Against Sars-Cov-2, Pharmaceutical Point of View, Biochimica et Biophysica Acta - General Subjects (2021)
14. Pharmacotherapeutic Considerations in Solid Organ Transplant Patients With Covid-19, Expert Opinion on Pharmacotherapy (2020)
15. Cinnamon and Its Possible Impact on Covid-19: The Viewpoint of Traditional and Conventional Medicine, Biomedicine and Pharmacotherapy (2021)
16. Real Clinical Practice and Therapeutic Management Following Covid-19 Crisis in Two Hospitals in Iran: A Statistical and Conceptual View, Tanaffos (2020)
17. Traditional Persian Medicine As a Holistic Therapeutic Approach for Managing Covid-19, Traditional Medicines and Natural Products as Preventive and Therapeutic Agents against COVID-19: a Promising Response to the Global Unprecedented Pandemic (2024)
18. Covid-19: General Strategies for Herbal Therapies, Journal of Evidence-Based Integrative Medicine (2022)
19. Nano Antiviral Photodynamic Therapy: A Probable Biophysicochemical Management Modality in Sars-Cov-2, Expert Opinion on Drug Delivery (2021)
20. Towards Treatment Planning of Covid-19: Rationale and Hypothesis for the Use of Multiple Immunosuppressive Agents: Anti-Antibodies, Immunoglobulins, and Corticosteroids, International Immunopharmacology (2020)