Transplantation Publisher



Farshbafnadi M^{1, 2} ; Razi S^{2, 3, 4} ; Rezaei N^{4, 5, 6}
Source: Clinical Immunology Published:2022

Abstract

Transplantation is a procedure in which cells, tissues, or organs of an individual are replaced by those of another individual or the same person. This procedure has saved the lives of many people since its implementation in medicine. Patients with end-stage organ failure and certain autoimmune diseases or malignancies that would have died otherwise have extended lives, and in some cases, been cured. However, complications such as infection, graft rejection, and graft failure have long existed that affected the lives of the patients following transplantation. Immunosuppressive methods and certain pre-transplant and post-transplant measures have been undertaken and have been successful to improve the quality of life and survival rates of the patients. However, they are still being developed to reach optimal results. The demand for organ transplantation is on the rise, and this leads to extended waiting lists. This issue has affected the criteria for organ transplantation and continues to do so to increase patients’ overall survival rates. © 2023 Elsevier Inc. All rights reserved.