Signal Amplification Strategy Using Gold/N-Trimethyl Chitosan/Iron Oxide Magnetic Composite Nanoparticles As a Tracer Tag for High-Sensitive Electrochemical Detection

Signal Amplification Strategy Using Gold/N-Trimethyl Chitosan/Iron Oxide Magnetic Composite Nanoparticles As a Tracer Tag for High-Sensitive Electrochemical Detection Publisher Pubmed

Shirazi H^{1, 2} ; Ahmadi A² ; Darzianiazizi M² ; Kashanian S² ; Kashanian S² ; Omidfar K^{1, 2, 4}

Source: IET Nanobiotechnology Published:2016

Abstract

This study presents a novel signal amplification method for high-sensitive electrochemical immunosensing. Gold (Au)/N-trimethyl chitosan (TMC)/iron oxide (Fe3O4) (shell/shell/core) nanocomposite was used as a tracing tag to label antibody. The tag was shown to be capable of amplifying the recognition signal by high-density assembly of Au nanoparticles (NPs) on TMC/Fe3O4 particles. The remarkable conductivity of AuNPs provides a feasible pathway for electron transfer. The method was found to be simple, reliable and capable of high-sensitive detection of human serum albumin as a model, down to 0.2 pg/ml in the range of 0.25-1000 pg/ml. Findings of the present study would create new opportunities for sensitive and rapid detection of various analytes. © The Institution of Engineering and Technology 2016.

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Style	Citing Format
MLA	Shirazi H, et al.. "Signal Amplification Strategy Using Gold/N-Trimethyl Chitosan/Iron Oxide Magnetic Composite Nanoparticles As a Tracer Tag for High-Sensitive Electrochemical Detection." IET Nanobiotechnology, vol. 10, no. 1, 2016, pp. 20-27.
APA	Shirazi H, Ahmadi A, Darzianiazizi M, Kashanian S, Kashanian S, Omidfar K (2016). Signal Amplification Strategy Using Gold/N-Trimethyl Chitosan/Iron Oxide Magnetic Composite Nanoparticles As a Tracer Tag for High-Sensitive Electrochemical Detection. IET Nanobiotechnology, 10(1), 20-27.
Chicago	Shirazi H, Ahmadi A, Darzianiazizi M, Kashanian S, Kashanian S, Omidfar K. "Signal Amplification Strategy Using Gold/N-Trimethyl Chitosan/Iron Oxide Magnetic Composite Nanoparticles As a Tracer Tag for High-Sensitive Electrochemical Detection." IET Nanobiotechnology 10, no. 1 (2016): 20-27.
Harvard	Shirazi H et al. (2016) 'Signal Amplification Strategy Using Gold/N-Trimethyl Chitosan/Iron Oxide Magnetic Composite Nanoparticles As a Tracer Tag for High-Sensitive Electrochemical Detection', IET Nanobiotechnology, 10(1), pp. 20-27.
Vancouver	Shirazi H, Ahmadi A, Darzianiazizi M, Kashanian S, Kashanian S, Omidfar K. Signal Amplification Strategy Using Gold/N-Trimethyl Chitosan/Iron Oxide Magnetic Composite Nanoparticles As a Tracer Tag for High-Sensitive Electrochemical Detection. IET Nanobiotechnology. 2016;10(1):20-27.
BibTex	@article{ author = {Shirazi H and Ahmadi A and Darzianiazizi M and Kashanian S and Kashanian S and Omidfar K}, title = {Signal Amplification Strategy Using Gold/N-Trimethyl Chitosan/Iron Oxide Magnetic Composite Nanoparticles As a Tracer Tag for High-Sensitive Electrochemical Detection}, journal = {IET Nanobiotechnology}, volume = {10}, number = {1}, pages = {20-27}, year = {2016} }
RIS	TY - JOUR AU - Shirazi H AU - Ahmadi A AU - Darzianiazizi M AU - Kashanian S AU - Kashanian S AU - Omidfar K TI - Signal Amplification Strategy Using Gold/N-Trimethyl Chitosan/Iron Oxide Magnetic Composite Nanoparticles As a Tracer Tag for High-Sensitive Electrochemical Detection JO - IET Nanobiotechnology VL - 10 IS - 1 SP - 20 EP - 27 PY - 2016 ER -

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