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Association of Adenovirus 36 Infection and Obesity; An Updated Meta-Analysis of Community-Based Studies Publisher Pubmed



Marjani A1 ; Khatami A2, 3 ; Saadati H4 ; Asghari M5 ; Razizadeh MH3 ; Abbasi A1 ; Zarei M6 ; Beikzadeh L7 ; Soleimani A8
Authors

Source: Reviews in Medical Virology Published:2022


Abstract

As a health problem, obesity has several risk factors; it has been suggested that human adenovirus type 36 (HAdV-36) infections may possibly be associated with obesity. This updated meta-analysis was designed and conducted with an emphasis on articles published from 2015 to 2020. The PubMed, Web of Science, and Scopus databases were searched up to 1 December 2020. Overall, pooled prevalence and odds ratio of antibodies against HAdV-36 in people with obesity and controls was assessed among different ages. Case-control and cohort studies were included in the analysis. The overall prevalence of HAdV-36 infection in obese population was 31% (CI: 0.24%–0.38%) which was 32% in cases and 27% in controls, respectively; a significant association was found between the cases and the controls (OR, 1.84; 95% CI, 1.39–2.43), especially in children younger than 18 years of age (OR, 2.44; 95% CI, 1.85–3.22). A significant association between adenovirus infection and obesity was found, especially in adolescents. © 2021 John Wiley & Sons Ltd.
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