Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Biomarker Sensing Using Luminescent Metal Nanoclusters Publisher



Tarokh A1 ; Hosseini M1, 2
Authors

Source: Luminescent Metal Nanoclusters: Synthesis# Characterization# and Applications Published:2022


Abstract

Metal nanoclusters (MNCs) as a special group of nanoparticles consisting of only a few atoms illustrate unique features for biomarker sensing. The outstanding optical, electrical, and reactivity properties of nanoclusters, besides their ultra-small size (typically less than 2nm), photostability, low toxicity, biocompatibility, and low photobleaching made them an eligible option for biological sensing applications. Some special properties of different MNCs (AgNC, AuNC, CuNP, PtNC, etc.) such as high photoluminescence, intense electrochemiluminescence, and unique physiochemical properties have opened up several new prospects for detecting important disease-related biomarkers. This chapter aims to provide insights into the development of nanocluster-based biosensing systems for the detection of some worthwhile biomarkers, which can lead to early diagnosis of different devastating diseases such as cancer and cardiovascular disease. © 2022 Elsevier Ltd. All rights reserved.
Related Docs
View other Related Docs
1. A Novel Dual-Mode and Label-Free Aptasensor Based Methodology for Breast Cancer Tissue Marker Targeting, Sensors and Actuators# B: Chemical (2020)
2. Challenges and Opportunities of Using Fluorescent Metal Nanocluster-Based Colorimetric Assays in Medicine, ACS Omega (2023)
3. Colorimetric and Energy Transfer Based Fluorometric Turn-On Method for Determination of Microrna Using Silver Nanoclusters and Gold Nanoparticles, Microchimica Acta (2018)
Experts (# of related papers)
Mehdi Khoobi (1)
Other Related Docs
4. Sensitive Detection of S. Aureus Using Aptamer- and Vancomycin -Copper Nanoclusters As Dual Recognition Strategy, Food Chemistry (2021)
5. A Colorimetric Paper Sensor for Citrate As Biomarker for Early Stage Detection of Prostate Cancer Based on Peroxidase-Like Activity of Cysteine-Capped Gold Nanoclusters, Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy (2019)
6. Fast and Selective Whole Cell Detection of Staphylococcus Aureus Bacteria in Food Samples by Paper Based Colorimetric Nanobiosensor Using Peroxidase-Like Catalytic Activity of Dna-Au/Pt Bimetallic Nanoclusters, Microchemical Journal (2020)
7. Detection of Large Deletion in Human Brca1 Gene in Human Breast Carcinoma Mcf-7 Cells by Using Dna-Silver Nanoclusters, Methods and Applications in Fluorescence (2018)
8. Fluorescence Based Turn-On Strategy for Determination of Microrna-155 Using Dna-Templated Copper Nanoclusters, Microchimica Acta (2017)
9. Novel Fluorometric Assay for Detection of Cysteine As a Reducing Agent and Template in Formation of Copper Nanoclusters, Journal of Fluorescence (2017)
10. A New Eye Dual-Readout Method for Mirna Detection Based on Dissolution of Gold Nanoparticles Via Lspr by Cdte Qds Photoinduction, Scientific Reports (2019)
11. Colorimetric and Fluorescent Dual-Biosensor Based on Zirconium and Preasodium Metal-Organic Framework (Zr/Pr Mof) for Mirna-191 Detection, Heliyon (2024)
12. A Colorimetric Assay of Dna Methyltransferase Activity Based on Peroxidase Mimicking of Dna Template Ag/Pt Bimetallic Nanoclusters, Analytical and Bioanalytical Chemistry (2018)
13. A New Fluorescence Turn-On Nanobiosensor for the Detection of Micro-Rna-21 Based on a Dna-Gold Nanocluster, Methods and Applications in Fluorescence (2017)
14. Fluorometric Determination of Microrna Via Fret Between Silver Nanoclusters and Cdte Quantum Dots, Microchimica Acta (2017)
15. Engineered Metal Nanoclusters in Nanobiomedicine and Clinical Diagnosis, (2025)
16. Visual Detection of Mirna Using Peroxidase-Like Catalytic Activity of Dna-Cuncs and Methylene Blue As Indicator, Clinica Chimica Acta (2018)
17. The Electrochemical Aptasensors for the Determination of Tumor Markers, Graphene Bioelectronics (2018)
18. Paper-Based Chemiluminescence and Colorimetric Detection of Cytochrome C by Cobalt Hydroxide Decorated Mesoporous Carbon, Microchemical Journal (2020)
19. Turn –On Fret-Based Cysteine Sensor by Sulfur-Doped Carbon Dots and Au Nanoparticles Decorated Ws2 Nanosheet, Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy (2022)
20. New Insight Into G-Quadruplexes; Diagnosis Application in Cancer, Analytical Biochemistry (2021)