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Biomaterials and Stem Cells As Drug/Gene-Delivery Vehicles for Parkinson's Treatment: An Update Publisher Pubmed



Roshani M1, 2 ; Kiaie N3 ; Aghdam RM1
Authors

Source: Regenerative Medicine Published:2021


Abstract

By introducing biomaterials and stem cells into Parkinson's disease (PD), therapeutic approaches have led to promising results due to facilitating brain targeting and blood-brain barrier permeation of the drugs and genes. Here, after reviewing the most recent drug-and gene-delivery vehicles including liposomes, exosomes, natural/synthetic polymeric particles/fibers, metallic/ceramic nanoparticles and microbubbles, used for Parkinson's disease treatment, the effect of stem cells as a reservoir of neurotrophic factors and exosomes is provided. © 2021 Future Medicine Ltd.
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