Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
A State-Of-The-Art Review on Solid Lipid Nanoparticles As a Nanovaccines Delivery System Publisher



Assefi M1 ; Ataeinaeini M2 ; Nazari A3 ; Gholipour A4 ; Vertizosores JJ5 ; Melody Callavasquez K6 ; Zuhair Talib Alnaqeeb B7 ; Hussein Jassim K8 ; Kalajahi HG9 ; Yasamineh S10 ; Dadashpour M11, 12
Authors

Source: Journal of Drug Delivery Science and Technology Published:2023


Abstract

In the design of vaccine generation, significant attempts have been made to produce novel vaccines and, as well, to increase the effectiveness of available vaccines versus particular diseases. Over the past few years, with nanovaccines, considerable attention has been paid to increasing vaccine effectiveness, immunization approaches, and targeted transfer to attain desirable immune reactions. Solid lipid nanoparticles (SLNs) are on the front line of the quickly advancing nanotechnology field with various powerful uses in the delivery of pharmaceutical, cosmetic active, and vaccine components, from small molecules to proteins and genes with different routes of administration. SLNs have become effective delivery techniques in vaccine generation. SLNs-based vaccines can increase site-specific transfer, antigen presentation, and triggering of innate immune reaction, strong T cell reaction, and harmlessness against infectious diseases, cancers, autoimmune diseases, and neurodegeneration. The present review will briefly explain the characteristics of SLNs and explore the other preparation methods and routes of administration, focusing on SLNs as a delivery system of the different vaccines. © 2023
1. Lipid-Based Nanoparticles for Drug Delivery Systems, Characterization and Biology of Nanomaterials for Drug Delivery: Nanoscience and Nanotechnology in Drug Delivery (2018)
3. Development of Nano-Carriers for Leishmania Vaccine Delivery, Expert Opinion on Drug Delivery (2020)
Experts (# of related papers)
Other Related Docs
6. A Concise Review on Cancer Treatment Methods and Delivery Systems, Journal of Drug Delivery Science and Technology (2019)
13. Toxicity Concerns of Nanocarriers, Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes (2017)
19. Marketed Antiparasitic Nanotechnology-Based Products and Drawbacks, Advances in Antiparasitic Therapies and Drug Delivery (2023)