Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Is Target-Based Drug Discovery Efficient? Discovery and “Off-Target” Mechanisms of All Drugs
Ismaeil Haririan
Ismaeil Haririan

Professor of Pharmaceutics

Department Pharmaceutical Biomaterials

School of Pharmacy

Medical Biomaterials Research Center

Tehran University of Medical Sciences

All Documents
1. Chondrogenic Potential of Pmscs Cultured on Chondroitin Sulfate/ Gelatin-Modified Dbm Scaffold, BioImpacts (2025)
2. Corrigendum to “Development of Silk Fibroin/Collagen Film Containing Gi-20 Peptide-Loaded Plga Nanoparticles Against Corneal Herpes Simplex Virus-1” [Int. J. Pharm. 669 (2025) 125022](S0378517324012560)(10.1016/J.Ijpharm.2024.125022), International Journal of Pharmaceutics (2025)
3. Development of a Bio-Inspired Phagocytic Stable Nanoghost With Anti-Inflammatory Properties for Management of Inflammation in Ulcerative Colitis, Journal of Drug Targeting (2025)
4. Development of Silk Fibroin/Collagen Film Containing Gi-20 Peptide-Loaded Plga Nanoparticles Against Corneal Herpes Simplex Virus-1, International Journal of Pharmaceutics (2025)
5. Property-Tailoring Chemical Modifications of Hyaluronic Acid for Regenerative Medicine Applications, Acta Biomaterialia (2025)
6. Retraction Notice to “A Novel Biocompatible Drug Delivery System of Chitosan/Temozolomide Nanoparticles Loaded Pcl-Pu Nanofibers for Sustained Delivery of Temozolomide” [International Journal of Biological Macromolecules 97 (2017) 744–751, (S0141813016327489), (10.1016/J.Ijbiomac.2017.01.073)], International Journal of Biological Macromolecules (2025)
7. A Deep Learning Model Based on the Bert Pre-Trained Model to Predict the Antiproliferative Activity of Anti-Cancer Chemical Compounds, SAR and QSAR in Environmental Research (2024)
8. A Deep Learning Model Based on the Bert Pre-Trained Model to Predict the Antiproliferative Activity of Anti-Cancer Chemical Compounds, SAR and QSAR in Environmental Research (2024)
9. A Doxycycline-Loaded Microfiber of Poly-Metformin/Pcl for Eradicating Melanoma Stem Cells, International Journal of Pharmaceutics (2024)
10. Biomaterials Coated With Zwitterionic Polymer Brush Demonstrated Significant Resistance to Bacterial Adhesion and Biofilm Formation in Comparison to Brush Coatings Incorporated With Antibiotics, Colloids and Surfaces B: Biointerfaces (2024)
11. Fabrication of a Controlled-Release Core-Shell Floating Tablet of Ketamine Hydrochloride Using a 3D Printing Technique for Management of Refractory Depressions and Chronic Pain, Polymers (2024)
12. Facile Fabrication of an Extended-Release Tablet of Ticagrelor Using Three Dimensional Printing Technology, Journal of Biomedical Materials Research - Part A (2024)
13. Self-Assembled Peptide/Polymer Hybrid Nanoplatform for Cancer Immunostimulating Therapies, Drug Delivery and Translational Research (2024)
14. Unveiling the Potential Role of Micro/Nano Biomaterials in the Treatment of Helicobacter Pylori Infection, Expert Review of Anti-Infective Therapy (2024)
15. Additive Manufacturing of an Extended-Release Tablet of Tacrolimus, Materials (2023)
16. An Anti-Inflammatory Glyburide-Loaded Nanoghost for Atherosclerosis Therapy: A Red Blood Cell Based Bio-Mimetic Strategy, Giant (2023)
17. Design and Fabrication of a High Performance Microfluidic Chip for Blood Plasma Separation: Modelling and Prediction of System Behaviour Via Cfd Method, International Journal of Analytical Chemistry (2023)
18. Factors Associated With Treatment Failure, and Possible Applications of Probiotic Bacteria in the Arsenal Against Helicobacter Pylori, Expert Review of Anti-Infective Therapy (2023)
19. Future Nanotechnology-Based Strategies for Improved Management of Helicobacter Pylori Infection, Small (2023)
20. Microfluidic Synthesis of Zoledronic Acid Loaded Chitosan Nanoparticles Used for Osteogenic Differentiation of Mesenchymal Cells, International Journal of Biological Macromolecules (2023)
21. Nanoarchitectonics of Doxycycline-Loaded Vitamin E-D-Α-Tocopheryl Polyethylene Glycol 1000 Succinate Micelles for Ovarian Cancer Stem Cell Treatment, Nanomedicine (2023)
22. Nanomedicine “New Food for an Old Mouth”: Novel Approaches for the Treatment of Covid-19, Drug Delivery Letters (2023)
23. Biomedical Applications of Silkworm (Bombyx Mori) Proteins in Regenerative Medicine (A Narrative Review), Journal of Tissue Engineering and Regenerative Medicine (2022)
24. Nanobiosensor Based on Sugar Code-Aunps Aggregation: A Key to Opening New Gates in Rapid Diagnosis of Streptococcal Pharyngitis, Frontiers in Bioengineering and Biotechnology (2022)
25. Targeting Pathophysiological Changes Using Biomaterials-Based Drug Delivery Systems: A Key to Managing Inflammatory Bowel Disease, Frontiers in Pharmacology (2022)
26. The Potential Use of Antibiotics Against Helicobacter Pylori Infection: Biopharmaceutical Implications, Frontiers in Pharmacology (2022)
27. An Investigation Into the Polylactic Acid Texturization Through Thermomechanical Processing and the Improved D33 Piezoelectric Outcome of the Fabricated Scaffolds, Journal of Materials Research and Technology (2021)
28. Application of Bone and Cartilage Extracellular Matrices in Articular Cartilage Regeneration, Biomedical Materials (Bristol) (2021)
29. Potential Anticancer Activity of a New Pro-Apoptotic Peptide-Thioctic Acid Gold Nanoparticle Platform, Nanotechnology (2021)
30. Sugar Codes Conjugated Alginate: An Innovative Platform to Make a Strategic Breakthrough in Simultaneous Prophylaxis of Gerd and Helicobacter Pylori Infection, Drug Design# Development and Therapy (2020)
31. 3-Aryl Coumarin Derivatives Bearing Aminoalkoxy Moiety As Multi-Target-Directed Ligands Against Alzheimer's Disease, Chemistry and Biodiversity (2019)
32. Optimization of Electrospinning Parameters for Producing Silk Fibroin/Poly(Ethylene Oxide) Nanofibers Using D-Optimal Method, Journal of Natural Fibers (2019)
33. Protein Corona Variation in Nanoparticles Revisited: A Dynamic Grouping Strategy, Colloids and Surfaces B: Biointerfaces (2019)
34. Synthesis and Biological Evaluation of New N-Benzylpyridinium-Based Benzoheterocycles As Potential Anti-Alzheimer's Agents, Bioorganic Chemistry (2019)
35. Continuous Nanoparticles Production Through a Combination of a Micro Electro Mechanical System and an Electromagnetic Resonator Cavity, Particulate Science and Technology (2018)
36. Curcumin-Lipoic Acid Conjugate As a Promising Anticancer Agent on the Surface of Gold‑Iron Oxide Nanocomposites: A Ph-Sensitive Targeted Drug Delivery System for Brain Cancer Theranostics, European Journal of Pharmaceutical Sciences (2018)
37. Electrospun Biocompatible Poly (Ε-Caprolactonediol)-Based Polyurethane Core/Shell Nanofibrous Scaffold for Controlled Release of Temozolomide, International Journal of Polymeric Materials and Polymeric Biomaterials (2018)
38. Fabrication and Characterization of Electrospun Laminin-Functionalized Silk Fibroin/Poly(Ethylene Oxide) Nanofibrous Scaffolds for Peripheral Nerve Regeneration, Journal of Biomedical Materials Research - Part B Applied Biomaterials (2018)
39. Glutathione Conjugated Polyethylenimine on the Surface of Fe 3 O 4 Magnetic Nanoparticles As a Theranostic Agent for Targeted and Controlled Curcumin Delivery, Journal of Biomaterials Science# Polymer Edition (2018)
40. A Novel Biocompatible Drug Delivery System of Chitosan/Temozolomide Nanoparticles Loaded Pcl-Pu Nanofibers for Sustained Delivery of Temozolomide, International Journal of Biological Macromolecules (2017)
41. An Investigation of Electrospun Henna Leaves Extract-Loaded Chitosan Based Nanofibrous Mats for Skin Tissue Engineering, Materials Science and Engineering C (2017)
42. Curcumin-Loaded Nanoliposomes Linked to Homing Peptides for Integrin Targeting and Neuropilin-1- Mediated Internalization, Pharmaceutical Biology (2017)
43. Efficient Multicomponent Synthesis of 1,2,3-Triazoles Catalyzed by Cu(Ii) Supported on Pei@Fe3o4 Mnps in a Water/Peg300 System, Turkish Journal of Chemistry (2017)
44. Gold Coated Poly (Ε-Caprolactonediol) Based Polyurethane Nanofibers for Controlled Release of Temozolomide, Biomedicine and Pharmacotherapy (2017)
45. Synthesis of Novel Benzimidazole and Benzothiazole Derivatives Bearing a 1,2,3-Triazole Ring System and Their Acetylcholinesterase Inhibitory Activity, Journal of Chemical Research (2017)
46. The Sustained Delivery of Temozolomide From Electrospun Pcl-Diol-B-Pu/Gold Nanocompsite Nanofibers to Treat Glioblastoma Tumors, Materials Science and Engineering C (2017)
47. Synthesis and Structure-Activity Relationship Study of Tacrine-Based Pyrano[2,3-C]Pyrazoles Targeting Ache/Buche and 15-Lox, European Journal of Medicinal Chemistry (2016)
48. Tuning the Anticancer Activity of a Novel Pro-Apoptotic Peptide Using Gold Nanoparticle Platforms, Scientific Reports (2016)
49. Comparison of Adsorption and Photo-Fenton Processes for Phenol and Paracetamol Removing From Aqueous Solutions: Single and Binary Systems, Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy (2015)
50. Comparison Study of Phenol Degradation Using Cobalt Ferrite Nanoparticles Synthesized by Hydrothermal and Microwave Methods, Desalination and Water Treatment (2015)
51. Development of Carrier Free Montelukast Dry Powder Inhalation Formulation, Pharmazeutische Industrie (2015)
52. Erratum: Removal of Cu2+, Pb2+ and Cr6+ From Aqueous Solutions Using a Chitosan/Graphene Oxide Composite Nanofibrous Adsorbent (Rsc Advances (2015) 5 (16532-16539)), RSC Advances (2015)
53. Evaluation of Multilayer Coated Magnetic Nanoparticles As Biocompatible Curcumin Delivery Platforms for Breast Cancer Treatment, RSC Advances (2015)
54. Fabrication of Peo/Chitosan/Pcl/Olive Oil Nanofibrous Scaffolds for Wound Dressing Applications, Fibers and Polymers (2015)
55. Fabrication of Pla/Peg/Mwcnt Electrospun Nanofibrous Scaffolds for Anticancer Drug Delivery, Journal of Applied Polymer Science (2015)
56. Optimization of the Combined Adsorption/Photo-Fenton Method for the Simultaneous Removal of Phenol and Paracetamol in a Binary System, Microporous and Mesoporous Materials (2015)
57. Removal of Cu2+, Pb2+ and Cr6+ From Aqueous Solutions Using a Chitosan/Graphene Oxide Composite Nanofibrous Adsorbent, RSC Advances (2015)
58. Scientific Evaluation of Medicinal Plants Used for the Treatment of Abnormal Uterine Bleeding by Avicenna, Archives of Gynecology and Obstetrics (2015)
59. Simultaneous Degradation of Phenol and Paracetamol During Photo-Fenton Process: Design and Optimization, Journal of the Taiwan Institute of Chemical Engineers (2015)
60. Cell-Surface Glycosaminoglycans Inhibit Intranuclear Uptake But Promote Post-Nuclear Processes of Polyamidoamine Dendrimer-Pdna Transfection, European Journal of Pharmaceutical Sciences (2013)
61. Evaluation of Cationic Dendrimer and Lipid As Transfection Reagents of Short Rnas for Stem Cell Modification, International Journal of Pharmaceutics (2013)
62. Ciprofloxacin Loaded Alginate/Chitosan and Solid Lipid Nanoparticles, Preparation, and Characterization, Journal of Dispersion Science and Technology (2012)