Tehran University of Medical Sciences

Science Communicator Platform

Faculty Members have conducted research related to the Detection of Aberrant Methylated Sept9 and Ntrk3 Genes in Sporadic Colorectal Cancer Patients As a Potential Diagnostic Biomarker
Zahra Salehi
Zahra Salehi

Assistant Professor of Medical Immunology

Hematology, Oncology and Stem Cell Transplantation Research Center

Tehran University of Medical Sciences

Related Documents
1. Targeting Perk and Grp78 in Colorectal Cancer: Genetic Insights and Novel Therapeutic Approaches, European Journal of Pharmacology (2024)
All Documents
1. Concurrent Sigmoid Colon Adenocarcinoma Presenting With Cutaneous Adult T-Cell Leukemia/Lymphoma: A Rare Case Report, Infectious Agents and Cancer (2026)
2. Determinants of Change in Disease-Modifying Drugs in Patients With Multiple Sclerosis: A Registry-Based Study, Multiple Sclerosis and Related Disorders (2026)
3. Exome Sequencing and Molecular Modeling Reveal Novel Loci in Familial Multiple Sclerosis: The Importance of Btnl3 and Btnl8 in Disease Pathogenesis, Molecular Neurobiology (2026)
4. Increased Incidence of Diabetes Mellitus in Hematological Malignancies: A Systematic Review and Meta-Analysis, BMC Cancer (2026)
5. Micrornas As Potential Prognostic Biomarkers in Acute Lymphoblastic Leukemia: A Systematic Review, Meta-Analysis, and Bioinformatics Study, Systematic Reviews (2026)
6. Paraneoplastic Pemphigus Mimicking Stevens– Johnson Syndrome in a Patient With Multiple Myeloma: A Rare and Clinically Challenging Presentation, International Journal of Hematology-Oncology and Stem Cell Research (2026)
7. Plant-Based Diet Indices in Relation to Novel Cardiovascular Risk Factors, Major Adverse Cardiovascular Events, and Novel Anthropometric Indices in Patients With Type 2 Diabetes, Scientific Reports (2026)
8. Post-Transplant Cyclophosphamide As Graft-Versus-Host Disease Prophylaxis for Matched Related Donor Hematopoietic Stem Cell Transplantation in Acute Leukemia: A Systematic Review and Meta-Analysis, Hematology (United Kingdom) (2026)
9. Advancing the Therapeutic Effectiveness of Paclitaxel in Chronic Lymphocytic Leukemia Through the Simultaneous Inhibition of Notch1 and Sf3b1, Cancer Cell International (2025)
10. Artificial Intelligence in Metalloprotein Binding Site Prediction: A Systematic Review Bridging Bioinformatics and Biotechnology, International Journal of Biological Macromolecules (2025)
11. Bioinformatics Analysis Reveals Shared Molecular Pathways for Relationship Between Ulcerative Colitis and Primary Sclerosing Cholangitis, Genomics and Informatics (2025)
12. Comparative Diagnostic Performance of Flow Cytometry, Aspiration, and Biopsy With Immunohistochemistry in Plasma Cell Neoplasms, International Journal of Hematology-Oncology and Stem Cell Research (2025)
13. Comprehensive Analysis of the Bid Gene to Uncover the Role of Novel Alternative Splicing Isoforms in Colon Adenocarcinoma: A Systematic Review of Literature and Bioinformatics Analysis, Cancer Cell International (2025)
14. Correlation Between Phenotype and Coagulation Factor Activity Level in Rare Bleeding Disorders: A Systematic Review, Seminars in Thrombosis and Hemostasis (2025)
15. Deciphering the Role of Circrna-Mirna Networks in Multiple Sclerosis Pathogenesis Through Minimal Cut-Set Analysis, Discover Applied Sciences (2025)
16. Essential Thrombocythemia As an Initial Presentation of Polyneuropathy, Organomegaly, Endocrinopathy, M-Protein, Skin Changes Syndrome With Complete Response to the Bortezomib, Cyclophosphamide, Dexamethasone Regimen: A Case Report, Journal of Medical Case Reports (2025)
17. Exploring the Role of the Tgf-Β Signaling Pathway in Colorectal Precancerous Polyps Biochemical Genetics, Biochemical Genetics (2025)
18. From Multiple Sclerosis to Organ-Specific Autoimmune Disorders: Insights Into the Molecular and Clinical Implications of Comorbidity, Molecular Neurobiology (2025)
19. Incidence and Risk Factors of Hypothyroidism in Patients With Hematological Malignancies Compared to Healthy Population: A Systematic Review and Meta-Analysis, BMC Cancer (2025)
20. Incidence and Risk Factors of Hypothyroidism in Patients With Hematological Malignancies Compared to Healthy Population: A Systematic Review and Meta-Analysis, BMC Cancer (2025)
21. Pseudogenes As Potential Diagnostic, Prognostic and Therapeutic Biomarkers in Colorectal Cancer: A Systematic Review, Cancer Reports (2025)
22. Targeted Delivery of Microrna Sponge Short-Hairpin Rna Via Vir-Inspired Biotechnical Vector: Enhancing Cancer Therapy, Gene Expression The Journal of Liver Research (2025)
23. The Impact of Anxiety and Depression on Hematologic Malignancy Outcomes: A Systematic Review and Meta-Analysis, BMC Cancer (2025)
24. The Impact of Cyp3a4, Cyp3a5, and Abcb1 Polymorphisms on Cyclosporine Concentration in Leukemia Patients After Allogeneic Hematopoietic Stem Cell Transplantation, Clinical Transplantation (2025)
25. The Role of Autophagy in Cancer: From Molecular Mechanism to Therapeutic Window, Frontiers in Immunology (2025)
26. Toward Precision Medicine in Celiac Disease: Emerging Roles of Multiomics and Artificial Intelligence, Analytical Cellular Pathology (2025)
27. Combined Cancer Immunotherapy Based on Targeting Adenosine Pathway and Pd-1/Pdl-1 Axis, Expert Opinion on Therapeutic Targets (2024)
28. Comprehensive Analysis Identifies Endocrine Fibroblast Growth Factors As Promising Prognostic Markers for Colorectal Carcinoma, Scientific Reports (2024)
29. Comprehensive Multi-Omics Analysis Reveals Npc2 and Itgav Genes As Potential Prognostic Biomarkers in Gastrointestinal Cancers, Cancer Reports (2024)
30. Consanguineous Marriage Among Familial Multiple Sclerosis Subjects: A National Registry-Based Study, Heliyon (2024)
31. Consanguineous Marriage Among Familial Multiple Sclerosis Subjects: A National Registry-Based Study, Heliyon (2024)
32. Correction: Ubiquitin-Specific Proteases (Usps) in Leukemia: A Systematic Review (Bmc Cancer, (2024), 24, 1, (894), 10.1186/S12885-024-12614-X), BMC Cancer (2024)
33. Decoding Common Genetic Alterations Between Barrett's Esophagus and Esophageal Adenocarcinoma: A Bioinformatics Analysis, Heliyon (2024)
34. Differential Expression of Angiogenesis-Related Genes ‘Vegf’ and ‘Angiopoietin-1’ in Metastatic and Emast-Positive Colorectal Cancer Patients, Scientific Reports (2024)
35. Guca2a Dysregulation As a Promising Biomarker for Accurate Diagnosis and Prognosis of Colorectal Cancer, Clinical and Experimental Medicine (2024)
36. Identification of Common Hub Genes and Key Molecular Pathways Between Multiple Sclerosis and Urological Disorders, Translational Research in Urology (2024)
37. Il-2Rg As a Possible Immunotherapeutic Target in Crc Predicting Poor Prognosis and Regulated by Mir-7-5P and Mir-26B-5P, Journal of Translational Medicine (2024)
38. Immunologic Responses to the Third and Fourth Doses of Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2) Vaccines in Cell Therapy Recipients: A Systematic Review and Meta-Analysis, Virology Journal (2024)
39. Revealing Disease Subtypes and Heterogeneity in Common Variable Immunodeficiency Through Transcriptomic Analysis, Scientific Reports (2024)
40. Targeting Perk and Grp78 in Colorectal Cancer: Genetic Insights and Novel Therapeutic Approaches, European Journal of Pharmacology (2024)
41. Time-Dependent Molecular Changes Following Mdma-Induced Nephrotoxicity, Iranian Journal of Pharmaceutical Research (2024)
42. Ube2c: A Pan-Cancer Diagnostic and Prognostic Biomarker Revealed Through Bioinformatics Analysis, Cancer Reports (2024)
43. Ubiquitin-Specific Peptidases in Lymphoma: A Path to Novel Therapeutics, Frontiers in Pharmacology (2024)
44. Ubiquitin-Specific Proteases (Usps) in Leukemia: A Systematic Review, BMC Cancer (2024)
45. Camp-Pde Signaling in Copd: Review of Cellular, Molecular and Clinical Features, Biochemistry and Biophysics Reports (2023)
46. Editorial: Computational Methods for Multi-Omics Data Analysis in Cancer Precision Medicine, Frontiers in Genetics (2023)
47. Expression Analysis of Long Noncoding Rna-Malat1 and Interleukin-6 in Inflammatory Bowel Disease Patients, Iranian Journal of Allergy# Asthma and Immunology (2023)
48. Guanylate Cyclase-C Signaling Axis As a Theragnostic Target in Colorectal Cancer: A Systematic Review of Literature, Frontiers in Oncology (2023)
49. Identification of Lncpvt1 and Circpvt1 As Prognostic Biomarkers in Human Colorectal Polyps, Scientific Reports (2023)
50. Integrated Bioinformatics and Wet-Lab Analysis Revealed Cell Adhesion Prominent Genes Cdc42, Tagln and Gsn As Prognostic Biomarkers in Colonic-Polyp Lesions, Scientific Reports (2023)
51. Long Non‑Coding Rna Linc00460 Contributes As a Potential Prognostic Biomarker Through Its Oncogenic Role With Anxa2 in Colorectal Polyps, Molecular Biology Reports (2023)
52. Meta-Analysis of Integrated Chip-Seq and Transcriptome Data Revealed Genomic Regions Affected by Estrogen Receptor Alpha in Breast Cancer, BMC Medical Genomics (2023)
53. P38 Mapk Signaling in Chronic Obstructive Pulmonary Disease Pathogenesis and Inhibitor Therapeutics, Cell Communication and Signaling (2023)
54. The Controversial Effect of Smoking and Nicotine in Sars-Cov-2 Infection, Allergy# Asthma and Clinical Immunology (2023)
55. Agonist/Antagonist Compounds' Mechanism of Action on Estrogen Receptor-Positive Breast Cancer: A System-Level Investigation Assisted by Meta-Analysis, Informatics in Medicine Unlocked (2022)
56. Atopic Dermatitis: Molecular, Cellular, and Clinical Aspects, Molecular Biology Reports (2022)
57. Epidemiology of Familial Multiple Sclerosis in Iran: A National Registry-Based Study, BMC Neurology (2022)
58. Epidemiology of Familial Multiple Sclerosis in Iran: A National Registry-Based Study, BMC Neurology (2022)
59. Immunomodulatory Potential of Human Mesenchymal Stem Cells and Their Exosomes on Multiple Sclerosis, Advanced Pharmaceutical Bulletin (2022)
60. The Effects of Synbiotic Supplementation on Serum Anti-Inflammatory Factors in the Survivors of Breast Cancer With Lymphedema Following a Low Calorie Diet: A Randomized, Double-Blind, Clinical Trial, Nutrition and Cancer (2022)
61. Decreased Serum Levels of Interleukin-4 and Interleukin-21 in New Pemphigus Vulgaris Patients, But Not Chronic Patients With Inactive Disease Compared to Healthy Controls, Dermatology Practical and Conceptual (2021)
62. Exome Sequencing Reveals Novel Rare Variants in Iranian Familial Multiple Sclerosis: The Importance of Pold2 in the Disease Pathogenesis, Genomics (2021)
63. Proposed Minimal Essential Co-Expression and Physical Interaction Networks Involved in the Development of Cognition Impairment in Human Mid and Late Life, Neurological Sciences (2021)
64. Redox Imbalance in Crohn's Disease Patients Is Modulated by Azathioprine, Redox Report (2021)
65. Rna Sequencing of Cd4+ T Cells in Relapsing–Remitting Multiple Sclerosis Patients at Relapse: Deciphering the Involvement of Novel Genes and Pathways, Journal of Molecular Neuroscience (2021)
66. The Association of Ebv and Hhv-6 Viral Load With Different Nk and Cd8+ T Cell Subsets in the Acute Phase of Relapsing-Remitting Multiple Sclerosis, Cell Journal (2021)
67. The Challenges of Using Physical Restraint in Intensive Care Units in Iran: A Qualitative Study, Journal of the Intensive Care Society (2021)
68. An Integrative Bayesian Network Approach to Highlight Key Drivers in Systemic Lupus Erythematosus, Arthritis Research and Therapy (2020)
69. Decreased Serum Levels of Interleukin-17, Interleukin-23, Tgf-Β in Pemphigus Vulgaris Patients, and Their Association With Disease Phase, Dermatologic Therapy (2020)
70. Epidemiology of Familial Multiple Sclerosis: A Population-Based Study in Tehran During 1999–2018, Multiple Sclerosis and Related Disorders (2020)
71. Increased Level of Caspase-1 in the Serum of Relapsing-Remitting Multiple Sclerosis (Rrms) Patients, Iranian Journal of Allergy# Asthma and Immunology (2020)
72. Manipulated Mesenchymal Stem Cells Applications in Neurodegenerative Diseases, International Journal of Stem Cells (2020)
73. Mesenchymal Stem Cell-Derived Exosomes: A Promising Therapeutic Ace Card to Address Autoimmune Diseases, International Journal of Stem Cells (2020)
74. The Effects of Synbiotic Supplementation on Antioxidant Capacity and Arm Volumes in Survivors of Breast Cancer-Related Lymphedema, Nutrition and Cancer (2020)
75. The Effects of Synbiotic Supplementation on Serum Inflammatory Markers and Edema Volume in Breast Cancer Survivors With Lymphedema, EXCLI Journal (2020)
76. The Influence of Reactive Oxygen Species in the Immune System and Pathogenesis of Multiple Sclerosis, Autoimmune Diseases (2020)
77. The Inhibitory Effect of Melatonin on the Proliferation of Irradiated A549 Cell Line, Journal of Cancer Research and Therapeutics (2020)
78. Circulating Mesenchymal Stem Cells, Stromal Derived Factor (Sdf)-1 and Ip-10 Levels Increased in Clinically Active Multiple Sclerosis Patients But Not in Clinically Stable Patients Treated With Beta Interferon, Multiple Sclerosis and Related Disorders (2019)
79. Post-Infarct Morphine Treatment Mitigates Left Ventricular Remodeling and Dysfunction in a Rat Model of Ischemia-Reperfusion, European Journal of Pharmacology (2019)
80. Association of Nod-Like Receptor Protein-3 Single Nucleotide Gene Polymorphisms and Expression With the Susceptibility to Relapsing–Remitting Multiple Sclerosis, International Journal of Immunogenetics (2018)
81. Increased Circulating T Follicular Helper Cells in Iranian Children With Type I Diabetes, Iranian Journal of Allergy# Asthma and Immunology (2018)
82. Differential Frequency of Cd8+ T Cell Subsets in Multiple Sclerosis Patients With Various Clinical Patterns, PLoS ONE (2016)