Concomitant Presence of Jak2 V617f Mutation and Bcr-Abl Translocation in a Pregnant Woman With Polycythemia Vera

Concomitant Presence of Jak2 V617f Mutation and Bcr-Abl Translocation in a Pregnant Woman With Polycythemia Vera Publisher Pubmed

Toogeh G¹ ; Ferdowsi S² ; Naadali F³ ; Alimoghaddam K⁴ ; Ghavamzadeh A⁴ ; Shirkoohi R⁵ ; Ghaffari SH⁴

Source: Medical Oncology Published:2011

Abstract

In 2007, a 27-year-old woman presented with mild splenomegaly. Blood counts showed hemoglobin (Hb): 17.8 g/dl, HCT: 56% and Red blood cells: 6.45 × 10 12/L. Bone marrow examination disclosed a hypercellular marrow. Molecular analysis showed the presence of the JAK2 V617F mutation and BCR-ABL/BCR mRNA b3a2 transcript. A diagnosis of BCR-ABL-positive polycythemia vera (PV) was made. In 2009, she had nulipar pregnancy and treated with interferon-alpha. She delivered a healthy girl infant at 37 weeks. This case report suggests that in a PV pregnant woman with a concomitant presence of JAK2 V617F mutation and BCR-ABL translocation, the administration of interferon during the pregnancy could lead to a safe pregnancy and delivery. © 2010 Springer Science+Business Media, LLC.

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Style	Citing Format
MLA	Toogeh G, et al.. "Concomitant Presence of Jak2 V617f Mutation and Bcr-Abl Translocation in a Pregnant Woman With Polycythemia Vera." Medical Oncology, vol. 28, no. 4, 2011, pp. 1555-1558.
APA	Toogeh G, Ferdowsi S, Naadali F, Alimoghaddam K, Ghavamzadeh A, Shirkoohi R, Ghaffari SH (2011). Concomitant Presence of Jak2 V617f Mutation and Bcr-Abl Translocation in a Pregnant Woman With Polycythemia Vera. Medical Oncology, 28(4), 1555-1558.
Chicago	Toogeh G, Ferdowsi S, Naadali F, Alimoghaddam K, Ghavamzadeh A, Shirkoohi R, Ghaffari SH. "Concomitant Presence of Jak2 V617f Mutation and Bcr-Abl Translocation in a Pregnant Woman With Polycythemia Vera." Medical Oncology 28, no. 4 (2011): 1555-1558.
Harvard	Toogeh G et al. (2011) 'Concomitant Presence of Jak2 V617f Mutation and Bcr-Abl Translocation in a Pregnant Woman With Polycythemia Vera', Medical Oncology, 28(4), pp. 1555-1558.
Vancouver	Toogeh G, Ferdowsi S, Naadali F, Alimoghaddam K, Ghavamzadeh A, Shirkoohi R, et al.. Concomitant Presence of Jak2 V617f Mutation and Bcr-Abl Translocation in a Pregnant Woman With Polycythemia Vera. Medical Oncology. 2011;28(4):1555-1558.
BibTex	@article{ author = {Toogeh G and Ferdowsi S and Naadali F and Alimoghaddam K and Ghavamzadeh A and Shirkoohi R and Ghaffari SH}, title = {Concomitant Presence of Jak2 V617f Mutation and Bcr-Abl Translocation in a Pregnant Woman With Polycythemia Vera}, journal = {Medical Oncology}, volume = {28}, number = {4}, pages = {1555-1558}, year = {2011} }
RIS	TY - JOUR AU - Toogeh G AU - Ferdowsi S AU - Naadali F AU - Alimoghaddam K AU - Ghavamzadeh A AU - Shirkoohi R AU - Ghaffari SH TI - Concomitant Presence of Jak2 V617f Mutation and Bcr-Abl Translocation in a Pregnant Woman With Polycythemia Vera JO - Medical Oncology VL - 28 IS - 4 SP - 1555 EP - 1558 PY - 2011 ER -

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