An Unusual Case of Gastrointestinal Basidiobolomycosis Mimicking Colon Cancer; Literature and Review Publisher Pubmed



Mohammadi R¹ ; Ansari Chaharsoghi M³ ; Khorvash F⁴ ; Kaleidari B⁵ ; Sanei MH⁶ ; Ahangarkani F² ; Abtahian Z⁷ ; Meis JF^{8, 9} ; Badali H¹⁰
Source: Journal de Mycologie Medicale Published:2019

Abstract

Gastrointestinal basidiobolomycosis (GIB), a rare fungal infection associated with high mortality, has been reported worldwide mainly from tropical and subtropical regions of Asia, USA, and Latin America. The clinical manifestations are highly diverse and non-specific depending on the underlying disease, but fever, abdominal pain, weight loss, diarrhea, constipation and chills have been observed. There are no prominent risk factors for GIB but climatic conditions and life style are related to this infection in arid and semi-arid regions. Therefore timely diagnosis and early treatment is a challenge. Herein, we present an unusual case of gastrointestinal basidiobolomycosis in a 54-year-old male, initially misdiagnosed as colon cancer. After follow-up, no evidence of relapse and the patient was successfully cured by liposomal amphotericin B. In addition, the differential diagnosis and histopathological findings are discussed with a review of the literature. © 2018 Elsevier Masson SAS