Lipid Profile in Patients With Ischemic and Hemorrhagic Stroke



Saadatnia M¹ ; Feiz M² ; Ziaei SE² ; Hamzeh M² ; Ghorbani E² ; Keshteli AH³
Source: Journal of Isfahan Medical School Published:2011

Abstract

Background: Globally, stroke is the second leading cause of death. The aim of the present study was to determine the lipid profile in a group of Iranian patients with ischemic and hemorrhagic stroke. Methods: This study was performed in Alzahra University Hospital (Isfahan, Iran) in 2007. We included subjects with proved ischemic and hemorrhagic stroke. Blood samples were drawn within 24 h of admission for measurement of triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL)-cholesterol, and low-density lipoprotein (LDL)-cholesterol. Data were analyzed by Student t-test and Mann-Whitney U test. Finding: Two hundred and fifty one patients were included (129 Men and 122 women). Mean age was 69.97 ± 10.63 years. There were 207 patients with ischemic stroke and 44 cases of hemorrhagic stroke. TG was higher in patients with ischemic stroke than in cases with hemorrhagic stroke (133.91 ± 67.84 mg/dl vs. 112.86 ± 40.92 mg/dl, P < 0.01). Patients with hemorrhagic stroke had higher levels of HDL than ones with ischemic stroke (55.43 ± 77.76 mg/dl vs. 39.78 ± 10.52 mg/dl, P < 0.01). LDL was higher in patients with hemorrhagic stroke than in cases with ischemic stroke (131.36 ± 45.98 mg/dl vs. 116.94 ± 40.02 mg/dl, P < 0.05). Mean TC did not differ significantly in two groups of patients. Conclusion: According to the present study patients with hemorrhagic stroke have higher HDL and LDL levels than ones with ischemic stroke. In contrast, TG is found to be higher in ischemic stroke cases than patients with hemorrhagic stroke.