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The Beneficial Property of Hydroalcoholic Extract of Annab on Burn Healing



Ansari Samani R1 ; Baradaran A2 ; Esmaeli E1 ; Shahinfard N1 ; Parvin N1 ; Namjoo AR3 ; Shirzad H1 ; Rafieiankopaei M1
Authors

Source: Life Science Journal Published:2012

Abstract

It has been suggested that Annab (Zizipus vulgaris L.) might be beneficial on burn healing, but there is not any evidence in literature for this effect of the plant. This study was carried out to evaluate the effect of hydroalcoholic extract of Annab on burn healing. In this study wounds were made by placing a hot plate with a surface area of 1.5 cm2 on the back of animals, for 10s. Forty mice were designated in four groups and treated with vehicle or test substance two times per day for 21 days. The first group received nothing, the second group received Vaseline, the third and fourth groups received 1% and 10% Annab ointment two times/day, respectively. The percentage of burn healing and the total time required for complete healing was evaluated. Results showed that 1% dose of Annab extract had significant burn healing compared to control group (P<0.01). Annab has considerable effect on burn wounds and its usage might be beneficial in these patients.
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