New Jatrophane Diterpenes From Euphorbia Osyridea With Proapoptotic Effects on Ovarian Cancer Cells

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New Jatrophane Diterpenes From Euphorbia Osyridea With Proapoptotic Effects on Ovarian Cancer Cells Publisher

Ghanadian M¹ ; Saeidi H² ; Aghaei M³ ; Rahiminejad MR² ; Ahmadi E² ; Ayatollahi SM⁴ ; Choudhary MI^{5, 6} ; Bahmani B³

Source: Phytochemistry Letters Published:2015

Abstract

Abstract A dichloromethane-acetone extract of Euphorbia osyridea Bioss. (Syn. Euphorbia lateriflora Schumach. & Thonn), a spurge endemic to Iran and West Africa, afforded three new jatrophane diterpenes belonging to the 2,3,5,7,8,9,14,15-octahydroxy-jatropha-6(17),11E-diene class along with three known triterpenes. Structures of these compounds were elucidated by spectroscopic methods, especially 2D NMR analyses. Biological effects of these compounds were analyzed by performing MTT and annexin V-FITC and PI staining assays against different cancer cell lines. Results showed that 2,3,5,7,8,9,14,15-octahydroxy-jatropha-6(17), 11E-diene derivatives (1-3) inhibit the cell proliferation through apoptosis in the Caov-4 and OVCAR-3 cancer cell lines. © 2015 Phytochemical Society of Europe.

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Style	Citing Format
MLA	Ghanadian M, et al.. "New Jatrophane Diterpenes From Euphorbia Osyridea With Proapoptotic Effects on Ovarian Cancer Cells." Phytochemistry Letters, vol. 12, no. , 2015, pp. 302-307.
APA	Ghanadian M, Saeidi H, Aghaei M, Rahiminejad MR, Ahmadi E, Ayatollahi SM, Choudhary MI, Bahmani B (2015). New Jatrophane Diterpenes From Euphorbia Osyridea With Proapoptotic Effects on Ovarian Cancer Cells. Phytochemistry Letters, 12(), 302-307.
Chicago	Ghanadian M, Saeidi H, Aghaei M, Rahiminejad MR, Ahmadi E, Ayatollahi SM, Choudhary MI, Bahmani B. "New Jatrophane Diterpenes From Euphorbia Osyridea With Proapoptotic Effects on Ovarian Cancer Cells." Phytochemistry Letters 12, no. (2015): 302-307.
Harvard	Ghanadian M et al. (2015) 'New Jatrophane Diterpenes From Euphorbia Osyridea With Proapoptotic Effects on Ovarian Cancer Cells', Phytochemistry Letters, 12(), pp. 302-307.
Vancouver	Ghanadian M, Saeidi H, Aghaei M, Rahiminejad MR, Ahmadi E, Ayatollahi SM, et al.. New Jatrophane Diterpenes From Euphorbia Osyridea With Proapoptotic Effects on Ovarian Cancer Cells. Phytochemistry Letters. 2015;12():302-307.
BibTex	@article{ author = {Ghanadian M and Saeidi H and Aghaei M and Rahiminejad MR and Ahmadi E and Ayatollahi SM and Choudhary MI and Bahmani B}, title = {New Jatrophane Diterpenes From Euphorbia Osyridea With Proapoptotic Effects on Ovarian Cancer Cells}, journal = {Phytochemistry Letters}, volume = {12}, number = {}, pages = {302-307}, year = {2015} }
RIS	TY - JOUR AU - Ghanadian M AU - Saeidi H AU - Aghaei M AU - Rahiminejad MR AU - Ahmadi E AU - Ayatollahi SM AU - Choudhary MI AU - Bahmani B TI - New Jatrophane Diterpenes From Euphorbia Osyridea With Proapoptotic Effects on Ovarian Cancer Cells JO - Phytochemistry Letters VL - 12 IS - SP - 302 EP - 307 PY - 2015 ER -

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