The Relationship Between Anthropometric Indices and Breast Cancer in Central Iran Publisher Pubmed

Summary: Postmenopausal women with higher waist-hip ratio face increased breast cancer risk; higher obesity index linked to lower risk. #BreastCancer #Anthropometry

Taleban R¹ ; Sirous R² ; Sirous M³ ; Razavi S⁴ ; Taghvaei R⁵ ; Sirous S⁶ ; Khalighinejad F¹ ; Dehghani Firouzabadi A⁷ ; Qobadi M⁷ ; Dehghani Firouzabadi F⁸ ; Moafi M⁹ ; Zand K¹⁰ ; Farajzadegan Z¹
Source: Nutrition and Cancer Published:2019

Abstract

Background: Anthropometric indices have a debatable relationship with breast cancer (BC) among different ethnicity. In the current study, we have evaluated the relationship between anthropometric indices and BC in Iranian participants. Methods: Between 2012 and 2014, a total of 7,805 women were enrolled from different mammography centers in Isfahan province, Iran. For each participant, a detailed questionnaire was filled out and anthropometric indices were measured by trained technicians. We used logistic regression models to estimate odds ratios (OR) and 95% confidence interval (CI) for BC risk associated with anthropometry measurements, stratified on menopausal status. Results: In the postmenopausal group, weight ≥68 kg compared to weight <61.75 kg was associated with decreased risk of BC (OR = 0.78; 95% CI: 0.63–0.97). Postmenopausal women with Waist-Hip Ratio (WHR) ≥ 0.85 compared to WHR < 0.77 were at increased risk of BC (OR = 1.36; 95% CI: 1.07–1.73). Both premenopausal and postmenopausal women had a decreased risk of BC with higher Obesity Index (OI) and Relative Weight. Conclusion: Ethnicity appears to play an important role in the discrepancies between results of different studies about the correlation of anthropometric features with BC. © 2019, © 2019 Taylor & Francis Group, LLC.