Platinum-Based Chemotherapies-Induced Nephrotoxicity: Mechanisms, Potential Treatments, and Management

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Platinum-Based Chemotherapies-Induced Nephrotoxicity: Mechanisms, Potential Treatments, and Management Publisher Pubmed

Shahrahmani F¹ ; Badamchizadeh S¹ ; Kaihani F² ; Alavimoghadam S¹ ; Keshtkari S³ ; Rezaeitavirani M⁴ ; Arjmand R¹ ; Larijani B⁵ ; Arjmand B¹

Source: International Urology and Nephrology Published:2025

Abstract

Platinum-based chemotherapies are essential in the treatment of several malignancies. However, such medications can damage the kidneys, frequently leading to both acute and chronic kidney disease. Treatment becomes more difficult for such problems. Physicians may alter chemotherapy regimens and utilize kidney-protecting medications to lessen renal damage. New imaging techniques and biomarkers also aid in the early detection of renal issues. To effectively handle the mentioned situation, oncologists, nephrologists, and pharmacists must collaborate. However, additional study is still required to develop customized therapies, discover strategies to minimize kidney injury and produce new platinum medicines. Hereupon, the present review's authors are being sought to address the causes, prospective treatments, and management of nephrotoxicity caused by platinum-based chemotherapy. © The Author(s), under exclusive licence to Springer Nature B.V. 2024.

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Style	Citing Format
MLA	Shahrahmani F, et al.. "Platinum-Based Chemotherapies-Induced Nephrotoxicity: Mechanisms, Potential Treatments, and Management." International Urology and Nephrology, vol. 57, no. 5, 2025, pp. 1563-1583.
APA	Shahrahmani F, Badamchizadeh S, Kaihani F, Alavimoghadam S, Keshtkari S, Rezaeitavirani M, Arjmand R, Larijani B, Arjmand B (2025). Platinum-Based Chemotherapies-Induced Nephrotoxicity: Mechanisms, Potential Treatments, and Management. International Urology and Nephrology, 57(5), 1563-1583.
Chicago	Shahrahmani F, Badamchizadeh S, Kaihani F, Alavimoghadam S, Keshtkari S, Rezaeitavirani M, Arjmand R, Larijani B, Arjmand B. "Platinum-Based Chemotherapies-Induced Nephrotoxicity: Mechanisms, Potential Treatments, and Management." International Urology and Nephrology 57, no. 5 (2025): 1563-1583.
Harvard	Shahrahmani F et al. (2025) 'Platinum-Based Chemotherapies-Induced Nephrotoxicity: Mechanisms, Potential Treatments, and Management', International Urology and Nephrology, 57(5), pp. 1563-1583.
Vancouver	Shahrahmani F, Badamchizadeh S, Kaihani F, Alavimoghadam S, Keshtkari S, Rezaeitavirani M, et al.. Platinum-Based Chemotherapies-Induced Nephrotoxicity: Mechanisms, Potential Treatments, and Management. International Urology and Nephrology. 2025;57(5):1563-1583.
BibTex	@article{ author = {Shahrahmani F and Badamchizadeh S and Kaihani F and Alavimoghadam S and Keshtkari S and Rezaeitavirani M and Arjmand R and Larijani B and Arjmand B}, title = {Platinum-Based Chemotherapies-Induced Nephrotoxicity: Mechanisms, Potential Treatments, and Management}, journal = {International Urology and Nephrology}, volume = {57}, number = {5}, pages = {1563-1583}, year = {2025} }
RIS	TY - JOUR AU - Shahrahmani F AU - Badamchizadeh S AU - Kaihani F AU - Alavimoghadam S AU - Keshtkari S AU - Rezaeitavirani M AU - Arjmand R AU - Larijani B AU - Arjmand B TI - Platinum-Based Chemotherapies-Induced Nephrotoxicity: Mechanisms, Potential Treatments, and Management JO - International Urology and Nephrology VL - 57 IS - 5 SP - 1563 EP - 1583 PY - 2025 ER -

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