Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Efficacy of Probiotics for Managing Infantile Colic Due to Their Anti-Inflammatory Properties: A Meta-Analysis and Systematic Review Publisher



Shirazinia R1 ; Golabchifar AA1 ; Fazeli MR2
Authors

Source: Clinical and Experimental Pediatrics Published:2021


Abstract

Background: Infantile colic (IC) is excessive crying in otherwise healthy children. Despite vast research efforts, its etiology remains unknown. Purpose: Most treatments for IC carry various side effects. The collection of evidence may inform researchers of new strategies for the management and treatment of IC as well as new clues for understanding its pathogenesis. This review and metaanalysis aimed to evaluate the efficacy and possible mechanisms of probiotics for mananaging IC. Methods: Ten papers met the study inclusion and exclusion criteria, and the meta-analysis was conducted using Review Manager (RevMan) software and a random-effects model. Results: This meta-analysis revealed that probiotics are effective for treating infantile colic, while the review showed that this efficacy may be due to their anti-inflammatory effects. Conclusion: Probiotics may be an important treatment option for managing infantile colic due to their anti-inflammatory properties. © 2021 by The Korean Pediatric Society.
Related Docs
View other Related Docs
1. Synbiotic Therapy in Infantile Colic Resistant to Conservative Therapy: A Clinical Trial, Journal of Pediatric and Neonatal Individualized Medicine (2021)
2. Evaluation of the Efficacy of Probiotics in the Treatment of Infantile Colic; a Randomized, Double Blind; Placebo Controlled Trial, Acta Medica Iranica (2019)
3. Comparison of the Effect of Massage and Probiotic Consumption on Infantile Colic: A Randomized Clinical Trial, HAYAT (2022)
Experts (# of related papers)
View all Related Experts
Shekoufeh Nikfar (1)
Mohammad Ali Boroumand (1)
Other Related Docs
4. Isolation of Novel Probiotic Lactobacillus and Enterococcus Strains From Human Salivary and Fecal Sources, Frontiers in Microbiology (2020)
5. Investigating the Anti-Inflammatory Effects of High Molecular Weight Secretions From Limosilactobacillus Reuteri Ptcc 1655 on Lps-Stimulated Pma-Differentiated Thp-1 Cells, Journal of Applied Microbiology (2021)
6. The Effectiveness of Treatment With Probiotics in Helicobacter Pylori Eradication: Results From an Umbrella Meta-Analysis on Meta-Analyses of Randomized Controlled Trials, Food and Function (2023)
7. Antimicrobial Activity of Lactobacillus Spp. Isolated From Fecal Flora of Healthy Breast-Fed Infants Against Diarrheagenic Escherichia Coli, Jundishapur Journal of Microbiology (2015)
8. The Comparison of Food and Supplement As Probiotic Delivery Vehicles, Critical Reviews in Food Science and Nutrition (2016)
9. Effect of Infant Formula Supplemented With Prebiotics and Probiotics on Incidence of Respiratory Tract Infections: A Systematic Review and Meta-Analysis of Randomized Clinical Trials, Complementary Therapies in Medicine (2021)
10. The Effects of Prebiotic, Probiotic or Synbiotic Supplementation on Overweight/Obesity Indicators: An Umbrella Review of the Trials’ Meta-Analyses, Frontiers in Endocrinology (2024)
11. Effectiveness of Probiotics in Irritable Bowel Syndrome: Updated Systematic Review With Meta-Analysis, World Journal of Gastroenterology (2015)
12. The Effects of Probiotics, Prebiotics and Synbiotics on the Reduction of Ibd Complications, a Periodic Review During 2009–2020, Journal of Applied Microbiology (2021)
13. Clinical Efficacy of Probiotics in Prevention of Infectious Diseases Among Hospitalized Patients in Icu and Non-Icu Wards in Clinical Randomized Trials: A Systematic Review, Health Science Reports (2023)
14. The Effect of Probiotics in Prevention of Necrotising Enterocolitis in Preterm Neonates in Comparison With Control Group, Iranian Journal of Pediatrics (2017)
15. The Efficacy of Probiotics in Prevention of Urinary Tract Infection in Children: A Systematic Review and Meta-Analysis, Journal of Pediatric Urology (2017)
16. Probiotics Reduce the Risk of Antibiotic-Associated Diarrhea in Adults (18-64 Years) But Not the Elderly (>65 Years), Nutrition in Clinical Practice (2016)
17. Prophylactic Vs. Therapeutic Effect of Probiotics on the Inflammation Mediated by the Nf-Κb Pathway in Inflammatory Bowel Conditions, Biomedicines (2023)
18. The Effects of Probiotic Supplementation on Mental Health, Biomarkers of Inflammation and Oxidative Stress in Patients With Psychiatric Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Complementary Therapies in Medicine (2020)
19. The Role of Probiotic Supplementation in Inflammatory Biomarkers in Adults: An Umbrella Meta-Analysis of Randomized Controlled Trials, Inflammopharmacology (2023)
20. Effect of Probiotic and Synbiotic Supplementation on Inflammatory Markers in Health and Disease Status: A Systematic Review and Meta-Analysis of Clinical Trials, Clinical Nutrition (2020)