Tehran University of Medical Sciences

Science Communicator Platform

Share By
The Spike Protein Mutations and Its Effect on Sars-Cov-2 Pathogenesis Publisher



Zandi M1, 2 ; Soltani S1, 2 ; Sanami S3 ; Rasooli A4, 5
Authors

Source: Journal of Cellular and Molecular Anesthesia Published:2021


Abstract

The severe acute respiratory syndrome coronavirus 2 spike (S) glycoprotein facilitates receptor binding to initiate cell entry that is the critical initial step in the infection cycle. Due to S glycoprotein's pivotal role, in this review, we pointed to show potential functional and structural consequences of S glycoprotein and its variants, which has been related to increased viral load in humans with SARS-CoV-2 infection. © 2021 Journal of Cellular and Molecular Anesthesia. All rights reserved.
Related Docs
View other Related Docs
1. Severe Acute Respiratory Syndrome-Coronavirus-2 Spike (S) Protein Based Vaccine Candidates: State of the Art and Future Prospects, Reviews in Medical Virology (2021)
2. Sars-Cov-2: Current Trends in Emerging Variants, Pathogenesis, Immune Responses, Potential Therapeutic, and Vaccine Development Strategies, International Immunopharmacology (2021)
3. Overview of the Current Promising Approaches for the Development of an Effective Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2) Vaccine, International Immunopharmacology (2020)
Experts (# of related papers)
View all Related Experts
Ahmad Nejati (1)
Reza Afrisham (1)
Other Related Docs
4. Genomic Surveillance of Sars-Cov-2 Strains Circulating in Iran During Six Waves of the Pandemic, Influenza and other Respiratory Viruses (2023)
5. The Role of Viral and Host Mirnas in the Control, Progression and Possible Treatment of Covid-19 Disease, Journal of Payavard Salamat (2022)
6. Risk Factors for Adverse Outcomes of Covid-19 Patients: Possible Basis for Diverse Responses to the Novel Coronavirus Sars-Cov-2, Life Sciences (2021)
7. Immunopathological Similarities Between Covid-19 and Influenza: Investigating the Consequences of Co-Infection, Microbial Pathogenesis (2021)
8. Classification of Viral Proteins Expressed by the Sars-Cov-2 Genome, Acta Microbiologica Hellenica (2022)
9. The Situation of Small Molecules Targeting Key Proteins in Combatting Sars-Cov-2: Synthesis, Metabolic Pathway, Mechanism of Action, and Potential Therapeutic Applications, Mini-Reviews in Medicinal Chemistry (2022)
10. Precision Medicine in Infectious Disease, Precision Medicine in Clinical Practice (2022)
11. Insights Into the Sars-Cov2 Outbreak; the Great Global Challenge: A Mini Review, Journal of Cellular and Molecular Anesthesia (2020)
12. Covid-19: Our Current Knowledge of Epidemiology, Pathology, Therapeutic Approaches, and Diagnostic Methods, Anti-Cancer Agents in Medicinal Chemistry (2021)
13. An Overview on the Treatments and Prevention Against Covid-19, Virology Journal (2023)
14. Vaccine Design and Delivery Approaches for Covid-19, International Immunopharmacology (2021)
15. Can Anti-Parasitic Drugs Help Control Covid-19?, Future Virology (2022)
16. Vlp-Based Covid-19 Vaccines: An Adaptable Technology Against the Threat of New Variants, Vaccines (2021)
17. Molecular Variants of Sars-Cov-2: Antigenic Properties and Current Vaccine Efficacy, Medical Microbiology and Immunology (2022)
18. The Chimera of S1 and N Proteins of Sars-Cov-2: Can It Be a Potential Vaccine Candidate for Covid-19?, Expert Review of Vaccines (2022)
19. Bidirectional Association Between Covid-19 and the Environment: A Systematic Review, Environmental Research (2021)
20. Deep Learning Techniques and Covid-19 Drug Discovery: Fundamentals, State-Of-The-Art and Future Directions, Studies in Systems# Decision and Control (2021)