Diagnostic Approach to the Patients With Suspected Primary Immunodeficiency

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):

Share By

Diagnostic Approach to the Patients With Suspected Primary Immunodeficiency Publisher Pubmed

Tavakol M^{1, 2} ; Jamee M³ ; Azizi G^{1, 4} ; Sadri H^{1, 2} ; Bagheri Y⁵ ; Zakidizaji M⁶ ; Mahdavi FS³ ; Jadidiniaragh F⁷ ; Tajfirooz S⁸ ; Kamali AN⁹ ; Aghamahdi F^{1, 10} ; Noorian S¹⁰ ; Kojidi HT¹⁰ ; Mosavian M^{1, 11} Show All Authors

Tavakol M^{1, 2}
Jamee M³
Azizi G^{1, 4}
Sadri H^{1, 2}
Bagheri Y⁵
Zakidizaji M⁶
Mahdavi FS³
Jadidiniaragh F⁷
Tajfirooz S⁸
Kamali AN⁹
Aghamahdi F^{1, 10}
Noorian S¹⁰
Kojidi HT¹⁰
Mosavian M^{1, 11}
Matani R¹¹
Dolatshahi E¹²
Porrostami K⁸
Elahimehr N⁸
Fatemiabhari M⁸
Sharifi L¹³
Arjmand R¹⁴
Haghi S¹⁵
Zainaldain H⁴
Yazdani R⁴
Shaghaghi M¹⁶
Abolhassani H¹⁷
Aghamohammadi A⁴

Source: Endocrine# Metabolic and Immune Disorders - Drug Targets Published:2020

Abstract

Background and Objective: Primary immunodeficiency diseases (PIDs) are a group of more than 350 disorders affecting distinct components of the innate and adaptive immune systems. In this review, the classic and advanced stepwise approach towards the diagnosis of PIDs are simplified and explained in detail. Results: Susceptibility to recurrent infections is the main hallmark of almost all PIDs. However, non-infectious complications attributable to immune dysregulation presenting with lymphoproliferative and/or autoimmune disorders are not uncommon. Moreover, PIDs could be associated with misleading presentations including allergic manifestations, enteropathies, and malignancies. Conclusion: Timely diagnosis is the most essential element in improving outcome and reducing the morbidity and mortality in PIDs. This wouldn’t be possible unless the physicians keep the diagnosis of PID in mind and be sufficiently aware of the approach to these patients. © 2020 Bentham Science Publishers.

Related Docs

View other Related Docs

1. Common Variable Immunodeficiency: Epidemiology, Pathogenesis, Clinical Manifestations, Diagnosis, Classification, and Management, Journal of Investigational Allergology and Clinical Immunology (2020)

2. Autoimmune Disorders Associated With Common Variable Immunodeficiency: Prediction, Diagnosis, and Treatment, Expert Review of Clinical Immunology (2022)

3. Systematic Investigation for Underlying Causes of Recurrent Infections in Children: Surveillance of Primary Immunodeficiency, European Annals of Allergy and Clinical Immunology (2018)

Experts (# of related papers)

View all Related Experts

Nima Rezaei (11)

Arash Kalantari (3)

Other Related Docs

4. Approach to Genetic Diagnosis of Inborn Errors of Immunity Through Next-Generation Sequencing, Molecular Immunology (2021)

5. Clinical Implications of Systematic Phenotyping and Exome Sequencing in Patients With Primary Antibody Deficiency, Genetics in Medicine (2019)

6. Approach to the Management of Autoimmunity in Primary Immunodeficiency, Scandinavian Journal of Immunology (2017)

7. The Clinical and Immunological Features of Patients With Primary Antibody Deficiencies, Endocrine# Metabolic and Immune Disorders - Drug Targets (2018)

8. General Considerations, Pulmonary Manifestations of Primary Immunodeficiency Diseases (2018)

9. Global Systematic Review of Primary Immunodeficiency Registries, Expert Review of Clinical Immunology (2020)

10. Evaluation of the Frequency and Diagnostic Delay of Primary Immunodeficiency Disorders Among Suspected Patients Based on the 10 Warning Sign Criteria: A Cross-Sectional Study in Iran, Allergologia et Immunopathologia (2020)

11. Primary Immunodeficiency Diseases in Iran: Past, Present and Future, Archives of Iranian Medicine (2021)

12. The Middle East and North Africa Diagnosis and Management Guidelines for Inborn Errors of Immunity, Journal of Allergy and Clinical Immunology: In Practice (2023)

13. Next Generation Sequencing Data Analysis in Primary Immunodeficiency Disorders – Future Directions, Journal of Clinical Immunology (2016)

14. Selective Iga Deficiency: Epidemiology, Pathogenesis, Clinical Phenotype, Diagnosis, Prognosis and Management, Scandinavian Journal of Immunology (2017)

15. Clinical, Immunologic, and Genetic Spectrum of 696 Patients With Combined Immunodeficiency, Journal of Allergy and Clinical Immunology (2018)

16. Expanding Clinical Phenotype and Novel Insights Into the Pathogenesis of Icos Deficiency, Journal of Clinical Immunology (2020)

17. Histocompatibility Complex Status and Mendelian Randomization Analysis in Unsolved Antibody Deficiency, Frontiers in Immunology (2020)

18. Primary Antibody Deficiency in a Tertiary Referral Hospital: A 30-Year Experiment, Journal of Investigational Allergology and Clinical Immunology (2015)

19. Common Presentations and Diagnostic Approaches, Stiehm's Immune Deficiencies: Inborn Errors of Immunity (2020)

20. Inborn Errors of Immunity and Cancers, Cancer Immunology: A Translational Medicine Context# Second Edition (2020)

Style	Citing Format
MLA	Tavakol M, et al.. "Diagnostic Approach to the Patients With Suspected Primary Immunodeficiency." Endocrine# Metabolic and Immune Disorders - Drug Targets, vol. 20, no. 2, 2020, pp. 157-171.
APA	Tavakol M, Jamee M, Azizi G, Sadri H, Bagheri Y, Zakidizaji M, Mahdavi FS, Jadidiniaragh F, Tajfirooz S, Kamali AN, Aghamahdi F, Noorian S, Kojidi HT, Mosavian M, Matani R, Dolatshahi E, Porrostami K, Elahimehr N, Fatemiabhari M, ... Aghamohammadi A (2020). Diagnostic Approach to the Patients With Suspected Primary Immunodeficiency. Endocrine# Metabolic and Immune Disorders - Drug Targets, 20(2), 157-171.
Chicago	Tavakol M, Jamee M, Azizi G, Sadri H, Bagheri Y, Zakidizaji M, Mahdavi FS, et al.. "Diagnostic Approach to the Patients With Suspected Primary Immunodeficiency." Endocrine# Metabolic and Immune Disorders - Drug Targets 20, no. 2 (2020): 157-171.
Harvard	Tavakol M et al. (2020) 'Diagnostic Approach to the Patients With Suspected Primary Immunodeficiency', Endocrine# Metabolic and Immune Disorders - Drug Targets, 20(2), pp. 157-171.
Vancouver	Tavakol M, Jamee M, Azizi G, Sadri H, Bagheri Y, Zakidizaji M, et al.. Diagnostic Approach to the Patients With Suspected Primary Immunodeficiency. Endocrine# Metabolic and Immune Disorders - Drug Targets. 2020;20(2):157-171.
BibTex	@article{ author = {Tavakol M and Jamee M and Azizi G and Sadri H and Bagheri Y and Zakidizaji M and Mahdavi FS and Jadidiniaragh F and Tajfirooz S and Kamali AN and Aghamahdi F and Noorian S and Kojidi HT and Mosavian M and Matani R and Dolatshahi E and Porrostami K and Elahimehr N and Fatemiabhari M and Sharifi L and Arjmand R and Haghi S and Zainaldain H and Yazdani R and Shaghaghi M and Abolhassani H and Aghamohammadi A}, title = {Diagnostic Approach to the Patients With Suspected Primary Immunodeficiency}, journal = {Endocrine# Metabolic and Immune Disorders - Drug Targets}, volume = {20}, number = {2}, pages = {157-171}, year = {2020} }
RIS	TY - JOUR AU - Tavakol M AU - Jamee M AU - Azizi G AU - Sadri H AU - Bagheri Y AU - Zakidizaji M AU - Mahdavi FS AU - Jadidiniaragh F AU - Tajfirooz S AU - Kamali AN AU - Aghamahdi F AU - Noorian S AU - Kojidi HT AU - Mosavian M AU - Matani R AU - Dolatshahi E AU - Porrostami K AU - Elahimehr N AU - Fatemiabhari M AU - Sharifi L AU - Arjmand R AU - Haghi S AU - Zainaldain H AU - Yazdani R AU - Shaghaghi M AU - Abolhassani H AU - Aghamohammadi A TI - Diagnostic Approach to the Patients With Suspected Primary Immunodeficiency JO - Endocrine# Metabolic and Immune Disorders - Drug Targets VL - 20 IS - 2 SP - 157 EP - 171 PY - 2020 ER -