Paget Disease of the Vulva: Report 5 Cases and Literature Review Publisher



Behtash N¹ ; Sabet F² ; Izadimood N³ ; Karimizarchi M⁴
Source: Journal of Obstetrics# Gynecology and Cancer Research Published:2021

Abstract

Vulvar Paget’s disease is rare among patients with vulvar cancer. Commonly, this disease is presented in the vulva and seen in postmenopausal women. In this study, we reported five cases of vulvar Paget’s disease referred to Bahman Hospital, Tehran, Iran, from 2013 to 2019. The median age of patients diagnosed with Paget’s vulvar disease was 56.2 years (ranges from 52 to 62 years); the oncology history of patients was negative. All patients underwent surgery, including wide local excision, hemivulvectomy, and bilateral vulvectomy. Invasive disease was observed in three patients. Surgical margins in three patients were involved by Paget’s disease, and one recurrence (25%) was observed. Paget’s disease should be diagnosed and treated by surgery as soon as possible to avoid worsening the prognosis of patients and recurrence. © 2021, Farname Inc. All rights reserved.