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Challenges of Using Sodium-Glucose Transporter-2 (Sglt-2) Inhibitors in the Treatment of Gestational Diabetes and Its Safety Considerations During Pregnancy



Bandarian M1 ; Bandarian F2, 3
Authors

Source: Iranian Journal of Diabetes and Metabolism Published:2023

Abstract

Sodium-glucose transporter-2 (SGLT-2) inhibitors are a relatively new class of anti-diabetic drugs with potent effect in glycemic control and weight loss, as well as beneficial effects in the prevention and control of cardiac and renal complications in non-pregnant patients with type 2 diabetes. However, there is no enough clear and strong evidence about the beneficial or adverse effect of SGLT-2 inhibitors usage during pregnancy for management of gestational diabetes (GDM) in human. This short letter discusses challenges in application of SGLT-2 inhibitors in management of GDM. © 2023, Tehran University of Medical Sciences. All rights reserved.
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