Antimicrobial Activities of the Polypropylene Imine Dendrimer Aginst Bacteria Isolated From Rural Water Resources

Antimicrobial Activities of the Polypropylene Imine Dendrimer Aginst Bacteria Isolated From Rural Water Resources Publisher

Jebelli MA¹ ; Kalantar E² ; Maleki A¹ ; Izanloo H³ ; Gharibi F⁴ ; Daraei H¹ ; Hayati B¹ ; Ghasemi E⁵ ; Azari A⁶

Source: Jundishapur Journal of Natural Pharmaceutical Products Published:2015

Abstract

Background: Dendrimers are a new class of polymeric materials with the well-defined structure, composition and architecture. Owing to antibacterial properties of dendrimers, they can be used as alternative water and wastewater disinfection with the minimum adverse side effects. Objectives: The aim of the present study was to evaluate the antibacterial activity of second generation poly propylene imine (PPI- G2) dendrimer on predominant bacteria in drinking water resources. Materials and Methods: In this qualitative and interventional study, a total of 764 water samples were collected from rural areas in Qom Province, Iran, and bacteria were isolated and identified using standard procedures. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against gram-positive and gram-negative bacteria were determined according to clinical and laboratory standards institute (CLSI) guideline. Standard discs were prepared using different concentrations of dendrimer on Mueller-Hinton agar plates. Results: The most important isolated bacteria were Escherichia coli 37 (48.7%), Klebsiella oxytoca 12 (15.8%), Proteus mirabilis 3 (4%), Entrobacter aerogenes 8 (10.5%), Citrobacter freundii 4 (5.2%), Pseudomonas aeruginosa 5 (6.6%), Staphylococcus aureus 2 (2.6%), and Bacillus subtilis 5 (6.6%). Moreover, it was found that PPI-G2 showed more potent activity towards the gram-positive bacteria than the gram-negative ones. Conclusions: The PPI-G2 dendrimer with end amine groups exhibited a positive impact on the removal of dominant bacterial isolated strains. Therefore, it is possible to use these nanodendrimers as a safe and effective material for water disinfection in the future. © 2015, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences.

Related Docs

View other Related Docs

1. The Antibacterial Effect of G3-Poly-Amidoamine Dendrimer on Gram Negative and Gram Positive Bacteria in Aqueous Solutions, Desalination and Water Treatment (2018)

2. Comparative Efficacy of Hospital Disinfectants Against Nosocomial Infection Pathogens, Antimicrobial Resistance and Infection Control (2020)

3. Comparison of Susceptibility Testing Methods for Determining the Activity of Colistin Against Gram-Negative Bacilli of Clinical Origin, Journal of Medical Microbiology (2019)

Experts (# of related papers)

View all Related Experts

Esmaeil Mohammadnejad (1)

Abbas Bahador (1)

Style	Citing Format
MLA	Jebelli MA, et al.. "Antimicrobial Activities of the Polypropylene Imine Dendrimer Aginst Bacteria Isolated From Rural Water Resources." Jundishapur Journal of Natural Pharmaceutical Products, vol. 10, no. 3, 2015, pp. -.
APA	Jebelli MA, Kalantar E, Maleki A, Izanloo H, Gharibi F, Daraei H, Hayati B, Ghasemi E, Azari A (2015). Antimicrobial Activities of the Polypropylene Imine Dendrimer Aginst Bacteria Isolated From Rural Water Resources. Jundishapur Journal of Natural Pharmaceutical Products, 10(3), -.
Chicago	Jebelli MA, Kalantar E, Maleki A, Izanloo H, Gharibi F, Daraei H, Hayati B, Ghasemi E, Azari A. "Antimicrobial Activities of the Polypropylene Imine Dendrimer Aginst Bacteria Isolated From Rural Water Resources." Jundishapur Journal of Natural Pharmaceutical Products 10, no. 3 (2015): -.
Harvard	Jebelli MA et al. (2015) 'Antimicrobial Activities of the Polypropylene Imine Dendrimer Aginst Bacteria Isolated From Rural Water Resources', Jundishapur Journal of Natural Pharmaceutical Products, 10(3), pp. -.
Vancouver	Jebelli MA, Kalantar E, Maleki A, Izanloo H, Gharibi F, Daraei H, et al.. Antimicrobial Activities of the Polypropylene Imine Dendrimer Aginst Bacteria Isolated From Rural Water Resources. Jundishapur Journal of Natural Pharmaceutical Products. 2015;10(3):-.
BibTex	@article{ author = {Jebelli MA and Kalantar E and Maleki A and Izanloo H and Gharibi F and Daraei H and Hayati B and Ghasemi E and Azari A}, title = {Antimicrobial Activities of the Polypropylene Imine Dendrimer Aginst Bacteria Isolated From Rural Water Resources}, journal = {Jundishapur Journal of Natural Pharmaceutical Products}, volume = {10}, number = {3}, pages = {-}, year = {2015} }
RIS	TY - JOUR AU - Jebelli MA AU - Kalantar E AU - Maleki A AU - Izanloo H AU - Gharibi F AU - Daraei H AU - Hayati B AU - Ghasemi E AU - Azari A TI - Antimicrobial Activities of the Polypropylene Imine Dendrimer Aginst Bacteria Isolated From Rural Water Resources JO - Jundishapur Journal of Natural Pharmaceutical Products VL - 10 IS - 3 SP - EP - PY - 2015 ER -

Science Communicator Platform

Authors

Abstract